Cutaneous T-cell lymphomas (CTCLs) are rare extranodal non-Hodgkin’s characterised by pleomorphic skin lesions and distinct T-cell markers. The annual incidence of these non-Hodgkin’s lymphomas are approximately 0.2–0.8/100,000 and mycosis fungoides..
The various epigenetic mechanisms include DNA methylation, histone tail modifications, non-coding RNA functions, regulation of polycomb assembly proteins, and cofactor modifiers. DNA methylation and histone modifications are the primary contributors to cancer epigenetics machinery that eventually may cause ...