professional therapist in supportive therapy sessions. If you prefer not to see a therapist in your local community, you might consider online therapy sessions. Regardless of whether you see a therapist in person or online, there are many potential benefits to seeing a therapist when you’re goin...
d Schematic showing the inhibition of HMGCR resulting in increased levels of HMG-CoA that modify the local pool of FAS. Source data are provided as a Source Data file. Full size image Next, we performed western blotting and found that metformin treated cells had a singular HMGylation band ...
high throughput, and excellent coverage of diseased tissue.154,155Sprayable nanomedicines have been administered at the surgical site following tumor resection and functioned as an adjuvant treatment to prevent both local tumor recurrence and distant metastasis....
A variety of nanomaterials such as hollow polydopamine nanoparticles, iron-based upconversion nanoparticles (UCNP) and metal–organic frameworks (MOFs), exert their strong NIR absorption and photothermal effect or rely on the loaded photothermal agents to elevate local temperature of the tumor site and...
Serum albumin as a local therapeutic agent in cell therapy and tissue engineering. BioFactors. 2017;43:315–30. https://doi.org/10.1002/biof.1337. Article CAS PubMed Google Scholar Piao J, Zabierowski S, Dubose BN, Hill EJ, Navare M, Claros N, et al. Preclinical efficacy and safety...
Injectable thermosensitive hydrogel-based drug delivery system for local cancer therapy. Colloids Surf B Biointerfaces. 2021;200:111581. Article PubMed CAS Google Scholar Kotta S, Aldawsari HM, Badr-Eldin SM, Nair AB, Kaleem M, Dalhat MH. Thermosensitive hydrogels loaded with resveratrol ...
As a complex disease, the uncontrolled cancer cells grow within different tissues, causing local damage and inflammation. Surgery, radiotherapy, and chemotherapy are traditional therapeutic approaches to treat and control the processes of this disease2. However, they have some limitations, such as ...
Radiotherapy (RT) is delivered for purposes of local control, but can also exert systemic effect on remote and non-irradiated tumor deposits, which is called abscopal effect. The view of RT as a simple local treatment has dramatically changed in recent years, and it is now widely accepted th...
The following image processing parameters were set for the automated quantification of transduced RGCs and the eGFP fluorescence intensity: cell diameter (pixels): 20–60; local threshold radius: 60; Gaussian blur sigma: 3. Retinal sections were manually processed for co-localisation by switching ...
Additional work is needed to refine the method and investigate associated local and systemic immune responses prior to moving this approach into the clinical arena. IVI IVI is by the far the least invasive delivery route under consideration for treating IRD and may protect inherently thin and ...