Editorial: Gene therapy for hearing loss: from mechanism to clinicdoi:10.3389/fnins.2023.1235627GENE therapyHEARING disordersSENSORINEURAL hearing lossACOUSTIC nerveShengyu ZouWenwen LiuYu SunQingyin ZhengZuhong HeFrontiers in Neuroscience
SiRNA-mediated knock-down of NOX3: Therapy for hearing loss? (Review) Cisplatin is a widely used chemotherapeutic agent that causes significant hearing loss. Previous studies have shown that cisplatin exposure is associated w... LP Rybak,D Mukherjea,S Jajoo,... - 《Cellular & Molecular Life ...
2. Olusanya BO, Davis AC, Hoffman HJ. Hearing loss grades and the International classification of functioning, disability and health. Bulletin of the World Health Organization. 2019;97(10):725. 3. Ahmed H, Shubina-Oleinik O, Holt JR. Emerging gene therapies for genetic hearing loss. Journal ...
Hearing impairment has long been accepted as a fact of life for the aging population—an estimated 30 million Americans suffer from some degree of hearing loss. However, scientists have long observed that other animals—namely birds, frogs, and fish—have been shown to have the ability to regen...
"Overall, intratympanic methylprednisolone was shown to be not inferior to oral prednisone for treatment of idiopathic sudden sensorineural hearing loss. Noninferiority was also indicated for certain subgroups. Both oral and intratympanic treatments are safe but can cause unpleasantadverse effects. The co...
Rinri Therapeutics has been founded on pioneering research into regenerative cell therapy led by Professor Marcelo Rivolta at the University of Sheffield.
(including without limitation the investigational gene therapy DB-OTO for the treatment of congenital hearing loss and the other gene therapy programs discussed or referenced in this press release (collectively, “Regeneron’s Product Candidates”)), the extent to which the results...
Treating idiopathic sudden sensorineural hearing loss with injections of steroids directly into the ear appears to result in recovery of hearing that is not less than recovery obtained with the standard therapy of oral corticosteroids and may be a preferable treatment for some patients to avoid the ...
Ryan AF,Harris JP,Keithley EM.Immune-mediated hearing loss: basic mechanisms and options for therapy.Acta Oto laryngologica. 2002... AF Ryan,JP Harris,EM Keithley - Acta Oto-Laryngologica 被引量: 87发表: 2009年 Etanercept therapy for immune-mediated cochleovestibular disorders: preliminary results...
In recent years, the use of viral vectors for gene therapy in the inner ear has received increasing attention as a way to treat either acquired or hereditary sensorineural hearing loss (for review see refs1,2,3,4,5). The sensory epithelia of the inner ear are promising sites for viral t...