It appears that DNA replication in such temperature-resistant revertants depends on an extragenic mutation, pcbA, already present in the parent strain and not linked to any of the DNA polymerase loci. This allele allows DNA replication dependent on DNA polymerase I and bypasses a temperature-...
Additionally, no difference was revealed between melatonin and amitriptyline (1 RCT), sodium valproate (1 RCT) or propranolol (1 non-randomized study) with respect to their efficacy in adults with migraine, while melatonin was more effective than pizotifen (1 RCT). In children with migraine, ...
Propranolol With propranolol, 160 to 320 mg per day for six and 12 weeks, no patients had increased angina or nitroglycerin use, and there were no hospitalizations... RR Miller,HG Olson,EA Amsterdam,... - 《New England Journal of Medicine》 被引量: 115发表: 1975年 Prophylactic options in...
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In conclusion, therapeutic drug monitoring appears to be of benefit in antiarrhythmic therapy. However, its proper use depends on an intimate understanding of the concepts of effective and toxic ranges, as well as the pharmacokinetic parameters of each agent....
Long-Acting Propranolol (Inderal LA): Pharmacokinetics, Pharmacodynamics and Therapeutic Use Long-acting propranolol (Inderal LA) is a new formulation of propranolol that allows release of the drug in a controlled manner, so that the plasma concent... Amal,A.,Mishriki,... - 《Pharmacotherapy the...
The use of computational and network biology methods for the analysis of potential DDIs have been developed recently and provide a powerful tool for the analyses of a huge number of drug pairs in such a complicated case of polypharmacy in COVID-19 or post-COVID-19 patients with existing ...
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Current drugs used for clinical management of LC patients are based on general therapy (lifestyle intervention), control of etiological factors, and use of drugs that counteract the splanchnic and systemic vasodilation. Up to now, this is achieved mainly by the oral administration of non-selective...
[50,54,55]. The reason behind this high rate of agitation in COVID-19 patients is unclear; this could be related to the greater severity of COVID-19 lung injury and higher levels of ventilatory support, the frequent use of prone positioning, a relatively higher incidence of young ...