Introduction:Anticoagulation therapy is the mainstay for the management of patients with acute pulmonary embolism (PE) and achieving a timely time to therapeutic range (TTR) is important. We sought to determine the TTR in patients with acute PE referred for mechanical thrombectomy (MT) and the ...
Genes that are transcriptionally activated with rapid kinetics, without requiring de novo protein synthesis, by a range of stimuli including viral infection or various extracellular signals. Low-density lipoprotein receptor-related protein Members of this family of proteins are cell-surface receptors that...
The materials used to coat stents may be either synthetic (e.g. polyurethane, poly-L lactic acid) or naturally occurring substances (e.g. heparin, phosphorylcholine). In fact, the first drug-coated stent to receive both U.S. and European approval just arrived on the market in November 200...
More patients achieved initial aPTT in target range using the modified protocol, 55% vs 6%, p<0.001. Average aPTT during TH was 63 +/- 35 vs 131 +/- 57 sec, p<0.001. The dose required to achieve target PTT at any time during TH was 7.1 +/- 1 vs 6 +/- 1 Units/kg/hr, p=...
Samples were diluted based on previously measured sFlt-1/PLGF ratio (range: 1:5–1:100). Diluted serum samples were dispensed into the wells coated with anti-CD105 antibody and incubated for 2 h at room temperature, followed by incubation with a horseradish-peroxidase-conjugated antibody ...
Samples were diluted based on previously measured sFlt-1/PLGF ratio (range: 1:5–1:100). Diluted serum samples were dispensed into the wells coated with anti-CD105 antibody and incubated for 2 h at room temperature, followed by incubation with a horseradish-peroxidase-conjugated antibody ...
Heparin and warfarin characteristics are summarized inFigure 1. As an anticoagulant, heparin and its derivatives bind to ATIII, which inactivates factor Xa and IIa, affecting the intrinsic pathway, measured as prolonged PTT. The anticoagulant activity of heparin is associated with the formation of ...
This compound is highly active against Gram-negative microorganisms, with an intensity comparable to that of colistin and polymyxin B; however, it demonstrates a more extensive range of action, with some activity also against Gram-positive bacteria [29]. The use of a range of biophysical tools ...