This implies that both drugs possibly fall within the same class of the Biopharmaceutical Classification System (BCS) defined by USFDA. Additionally, the metabolic half-life (T1/2) of poyendarone is comparable to dronedarone. This implies that poyendarone preserves the metabolic stability of ...
Fig. 2. Classification of main forms of astrogliopathology. Reactive astrogliosis is the most studied and most known form of astrocytopathology; already >100 years ago it has been considered as an almost obligatory indicator of pathological process in the CNS [80,81]. Astrogliosis is an evolutio...
Supervised and unsupervised classification methods, such as discriminant, cluster and principal component analysis or other pattern recognition techniques [163] together with the integration of lipidomics with transcriptomics, proteomics and metabolomics [164] are introduced in order to understand the ...