This implies that both drugs possibly fall within the same class of the Biopharmaceutical Classification System (BCS) defined by USFDA. Additionally, the metabolic half-life (T1/2) of poyendarone is comparable t
Fig. 2. Classification of main forms of astrogliopathology. Reactive astrogliosis is the most studied and most known form of astrocytopathology; already >100 years ago it has been considered as an almost obligatory indicator of pathological process in the CNS [80,81]. Astrogliosis is an evolutio...
Supervised and unsupervised classification methods, such as discriminant, cluster and principal component analysis or other pattern recognition techniques [163] together with the integration of lipidomics with transcriptomics, proteomics and metabolomics [164] are introduced in order to understand the ...