Baclofen Baclofen is a selective GABAB receptor agonist; in particular, it can act presynaptically to hyperpolarize synaptic terminals, inhibiting the influx of calcium and preventing the release of the excitatory neurotransmitters glutamate and aspartate. It is used as an antispasticity agent in ...
We present a case of a 49-year-old female with exacerbation of SPS, in whom some standard pharmacotherapy could not be introduced (clonazepam, baclofen used in the past) and doses of existing standard medications could not be increased (diazepam, gabapentin, and levetiracetam) due to adverse ...
For patients who can not tolerate carbamazepine because of its adverse side effects (poor liver function, confusion, ataxia, drowsiness, and allergic responses), the literature indicates baclofen and other anticonvulsant drugs such as clonazepam (Klonopin) may be useful. Cryoanalgesia, cryotherapy, or...