However, the very same properties of heme that nature exploits to support life, including its redox activity, Lewis acidity, and hydrophobicity, also renders heme potentially cytotoxic [11]. Indeed, if inappropriately handled by cells, heme can catalyze deleterious redox reactions and/or become mis...
In the following section, ways through which lipids may theoretically impact or have been demonstrated to actually affect nuclear homeostasis are described (a simplified compilation of these roles can be found in blue font in the scheme presented in Figure 1). When justified, how this may uncover...