Komar AA. The Yin and Yang of codon usage. Hum Mol Genet 2016;25:R77-R85.Komar AA. The Yin and Yang of Codon Usage. Hum Mol Genet. 2016;R2:ddw207.Komar AA. The Yin and Yang of codon usage. Hum Mol Genet 2016; 25(R2):R77-R85....
The mutational robustness of the genetic code is rarely discussed in the context of biological diversity, such as codon usage and related factors, often considered as independent of the actual organism’s proteome. Here we put the living beings back to picture and use distortion as a metric of...
Protein stability is affected at different hierarchies – gene, RNA, amino acid sequence and structure. Gene is the first level which contributes via varying codon compositions. Codon selectivity of an organism differs with normal and extremophilic milie
To explore further the importance of codon usage in envelope protein expression, we replaced the codons of a small, typically highly expressed cell-surface protein, the rat Thy-1 antigen, with the codons most frequently used by the HIV-1 envelope protein. The resulting sequence was then edited...
Z Yan,WM Zhao,H Wang,YB Zhou,Xi Yang 摘要: Chlamydia trachomatis is a kind of obligate intracellular bacterial pathogen that causes ocular and sexually transmitted diseases. In this study, we analyzed the codon usage patterns of the C. trachomatis mouse pneumonitis biovar (MoPn) and Homo ...
Mesona chinensis Benth (MCB) is one of the main economic crops in tropical and subtropical areas. To understand the codon usage bias (CUB) in M. chinensis
and amino acid usage patterns in the genus. An extensive scrutiny of the factors underlying the complex modalities of codon and amino acid usage inUstilagohas been executed in the present analysis. Multivariate statistical analysis revealed a dominant effect of natural selection pressure, aimed at ...
While factors such as mutational pressure [6], [7], [8], translational selection [9], [10], [11], [12], and secondary structure of proteins [13], [14], [15], [16], [17] influence codon usage in various organisms, amino acid usage was shown to be governed by hydrophobicity, ...
We also examined codon usage, sequence repeats, RNA editing and selective pressure in the A. truncatum mitog- enome. To determine the evolutionary and taxonomic status of A. truncatum, we conducted a phylogenetic analysis based on the mitogenomes of A. truncatum and 25 other taxa. In ...
Interferon-armed RBD dimer enhances the immunogenicity of RBD for sterilizing immunity against SARS-CoV-2 Shiyu Sun, Yueqi Cai, Tian-Zhang Song, Yang Pu, Lin Cheng, Hairong Xu, Jing Sun, Chaoyang Meng, Yifan Lin, Haibin Huang, Fang Zhao, Silin Zhang, Yu Gao, Jian-Bao...