C.M. Koh, M. Bezzi, E. Guccione, The where and the how of PRMT5, Curr. Mol. Biol. Rep. 1 (2015) 19-28.Koh C, Bezzi M, Guccione E. The Where and the How of PRMT5. Curr Mol Bio Rep 2015; 1: 19-28.Koh CM, Bezzi M, Guceione E. The where and the how of PRMT5 [...
PRMT5 inhibits the transcription of CAMK2N1 by depositing the repressive histone marks H4R3me2s and H3R8me2s on the proximal promoter region of CAMK2N1, and results in malignant progression of PCa both in vitro and in vivo. Moreover, the expression of circSPON2, a candidate circRNA in ...
Pancreatic ductal adenocarcinoma (PDAC) is a common malignant tumor of the digestive tract. Although gemcitabine and other therapeutic agents are effective in patients with advanced and metastatic pancreatic cancer, drug resistance has severely limited t
Functionally, GCs are divided into the dark zone, a site of B-cell hyperproliferation where the B-cell receptor repertoire is shaped by somatic hypermutation, and the light zone, where B cells with high antigen affinity are selected for survival through cognate antigenic interactions.1,2 ...
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The coactivator associated arginine methyltransferase (CARM1) promotes transcription, as its name implies. It does so by modifying histones and chromatin bound proteins. We identified nuclear factor I B (NFIB) as a CARM1 substrate and show that this tran
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All the model checkpointsprovided by 🤗 Transformers are seamlessly integrated from the huggingface.comodel hub, where they are uploaded directly byusersandorganizations. Current number of checkpoints: 🤗 Transformers currently provides the following architectures (seeherefor a high-level summary of ea...
All the model checkpoints provided by 🤗 Transformers are seamlessly integrated from the huggingface.co model hub, where they are uploaded directly by users and organizations.Current number of checkpoints: 🤗 Transformers currently provides the following architectures (see here for a high-level ...