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Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves the precision and sensitivity of evolutionary inference, producing more robust results than single-genome analyses can provide. The genomes of 12 Drosophila specie
Small RNAs (sRNAs) within 15-30 nt such as miRNA, tsRNA, srRNA with 3’-OH have been identified. However, whether these sRNAs are the major 15-30 nt sRNAs is still unknown. Here we show about 90% mammalian sRNAs within 15-30 nt end with 2’,3’-cyclic ph
The primary cause of mortality in the USA and in most developed countries is cardiovascular disease (CVD), and it is the primary or secondary cause of death in the largest clinical trials ever conducted for preventing or treating breast cancer. The overa
The first generation of genome sequence assemblies and annotations have had a significant impact upon our understanding of the biology of the sequenced species, the phylogenetic relationships among species, the study of populations within and across species, and have informed the biology of humans. As...
I have html content with images. I am converting images to base64 format in the html string. Content is showing fine. But images are missing in the docx file. Please help me what I am doing wrong My html string like this let img= '<!--do...
SM-A87 has a full set of genes for glycolysis, the pentose phosphate pathway and the tricarboxylic/citric acid cycle. The strain has five predicted lactate dehydrogenases, two L- and three D-, and also contains predicted ethanol-producing enzymes including aldehyde dehydrogenase (ZPR_1384, ZPR_...
Glycoside hydrolases cleave the bond between a carbohydrate and another carbohydrate, a protein, lipid or other moiety. Genes encoding glycoside hydrolases are found in a wide range of organisms, from archea to animals, and are relatively abundant in pla
The results showed that metformin or alectinib alone slightly decreased the proliferation of H3122/HGF and H3122-AR3 cells and the colony formation of H3122/HGF cells, whereas the combination of the drugs significantly enhanced the inhibitory effect (Fig. 2c, d). Overall, these data suggest ...
Castration-resistant prostate cancer (CRPC) is an aggressive lethal form of prostate cancer (PCa). Atraric acid (AA) not only inhibits the wild-type androgen receptor (AR) but also those AR mutants that confer therapy resistance to other clinically used