In 2014, UK Biobank started the world's largest multi-modal imaging study, with the aim of re-inviting 100,000 participants to undergo brain, cardiac and abdominal magnetic resonance imaging, dual-energy X-ray absorptiometry and carotid ultrasound. The combination of large-scale multi-modal ...
UK Biobank is a population-based cohort of half a million participants aged 40–69 years recruited between 2006 and 2010. In 2014, UK Biobank started the world’s largest multi-modal imaging study, with the aim of re-inviting 100,000 participants to undergo brain, cardiac and abdominal magnet...
The UK Biobank is an unprecedented resource for human disease research. In March 2019, 49,997 exomes were made publicly available to investigators. Here we note that thousands of variant calls are unexpectedly absent from this dataset, with 641 genes showing zero variation. We show that the ...
Tim Sprousen, the UK Biobank Chief Scientist identified, it has already yielded one of its most important findings that should be noted by anyone undertaking collaborative research – research with people rather than on people. This is the finding he mentioned: that when people feel properly ...
Community of over 10,500 scientists globally, including 80% of the Top 20 Pharma. 41.3% US, 23.1% UK, and 12.1% APAC. 8900 projects created Discover the UK Biobank Research Analysis Platform The UK Biobank RAP, enabled by DNAnexus, is an all-in-one platform: secure, compliant cloud in...
First, it relied on publicly available GWAS summary statistics from the UK Biobank dataset for all the neuroimaging traits analyzed. Although this is a powerful resource and one of the largest and most homogeneous brain imaging genetics datasets to date23, the participants in this dataset are of ...
The UK Biobank project: trust and altruism are alive and well: a model for achieving public support for research using personal data. 来自 dx.doi.org 喜欢 0 阅读量: 32 作者: H Thornton 摘要: Department of Health Sciences, University of Leicester, Saionara, Rowhedge, Colchester, UK. ...
In recent years, there have been significant efforts across the UK life-sciences sector to help biotechs bridge the “valley of death” between academic innovation and commercialization. The United Kingdom’s Digital Innovation Hub has transformed local data from the UK Biobank, Genomi...
From the UK Biobank wrist accelerometry substudy activity data,5 we included only nonexercisers—participants who reported no leisure time exercise and 1 or fewer recreational walks per week4 (eTable 1 in Supplement 1). We excluded participants with missing covariates; prevalent cancer or previous...
摘要: Cathie Sudlow and colleagues describe the UK Biobank, a large population-based prospective study, established to allow investigation of the genetic and non-genetic determinants of the diseases of middle and old age.关键词: COPD pulmonary surfactant-associated protein A pulmonary surfactant-...