This review focuses on the therapeutic potential of apigenin against atherosclerosis as a key nutraceutical or therapeutic agent, as well as the mechanisms underlying its anti-atherogenic properties through in
Apigenin (APG), known for its antioxidant properties, holds potential as a therapeutic compound in ALS.We used the Tg(SOD1*G93A)1Gur/J transgenic mouse model of ALS to investigate the therapeutic effects of APG. Key measured included motor function via the ALSTDI score, molecular markers of...
The therapeutic potential of apigenin Int. J. Mol. Sci., 20 (2019), p. 1305, 10.3390/ijms20061305 View in ScopusGoogle Scholar Sato et al., 2020 N. Sato, Y. Yako, T. Maruyama, S. Ishikawa, K. Kuromiya, S.M. Tokuoka, et al. The COX-2/PGE2 pathway suppresses apical elimination...
Therapeutic potential of combined anti-IL-1β IgY and anti-TNF-α IgY in guinea pigs with allergic rhinitis induced by ovalbumin. Int Immunopharmacol. 2015;25:155-61. 71. Jin Q, Ren F, Dai D, Sun N, Qian Y and Song P. The causality between intestinal flora and allergic diseases: ...
Apigenin effectively suppressed angiogenesis in HG-induced HRMECs by modulating the miR-140-5p/HDAC3-mediated PTEN/PI3K/AKT pathway. Our study may contribute to the development of novel therapeutic approaches and identification of potential targets for the treatment of DR. ...
proliferating cells, thus confirming the feasibility of using this stromal line for further studies (Extended Data Fig.1b). Upon large-scale screening of the PDMA library, we identified several compounds with the potential to selectively kill senescent cells in culture (Extended Data Fig.1c–e)....
Anti-ageing potential of sirtuins: in vivo and in vitro studies Ageing is associated with numerous changes at the organismal, tissue as well as cellular level. With age, senescent cells accumulate in many tissues impairing their proper functioning. Senescent cells have a strong impact on surrounding...
Accumulating evidence supports the anti-oxidant and anti-inflammatory effects of polyphenols, including phenylpropanoids and its sub-classes of flavonoids, sinapate esters and hydroxycinnamic acids, suggesting a potential role in a therapeutic approach to human inflammation-related diseases1,2, including neur...
Many compounds have been shown to exhibit a series of beneficial effects for the treatment of NAFLD, including anti-oxidative and anti-inflammatory functions, improvement of lipid metabolism and reversal of insulin resistance. In this review, we summarize potential therapeutic effects of TCM formulas ...
This study was aimed to discover key Chinese materia medica, main active compounds, hub therapeutic target proteins and core signal pathways in the potential therapeutic mechanism of HSBD on severe COVID-19 through integrating network pharmacological methods. Experimental procedure TCMSP, TCMID and ...