We develop an effective theory approach to investigate the phase properties of globular proteins. Instead of interactions between individual atoms or localized interaction centers, the approach builds directly on the tertiary structure of a protein. As an example we construct the phase diagram of (apo...
<p>To answer the question "Which type of bonds stabilize the tertiary structure of a protein?", we can break down the solution into the following steps:</p><p>1. <strong>Understanding Protein Structure</strong>: - Proteins are large macromolecules mad
Protein Organization:Proteins are organized into four different levels of organization. The protein levels of organization are primary, secondary, tertiary and quaternary structures.Answer and Explanation: Become a member and unlock all Study Answers Start today. Try it now ...
Predicting the tertiary structure of protein from its primary amino acid sequence is a challenging mission for bioinformatics. In this paper we proposes a novel approach of predicting the tertiary structure of protein using the flexible neural tree (FNT) to construct a tree classification model. Two...
of a stabilized protein tertiary structure that acts as an inhibitor of the interaction between the transcription factor TEAD and its co-repressor VGL4, both playing a central role in the Hippo signalling pathway. Modification of the inhibitor with a cell-penetrating entity yielded a cell-permeable...
Describe the structure, function, and properties of enzymes. Discuss the functions that proteins have. What determines protein function? Enzymes are proteins. Define a protein and explain how the tertiary structure of a protein determines the protein's overall shape and function. ...
Tertiary structuredescribes all aspects of the three-dimensional folding of a polypeptide When a protein has two or more polypeptide subunits, their arrangement in space is referred to asquaternary structure Ⅱ. The Function of a Protein Depends on Its Amino Acid Sequence ...
The packing of α-helices and β-sheets in six αβ proteins (e.g. flavodoxin) has been analysed. The results provide the basis for a computer algorithm to predict the tertiary structure of an αβ protein from its amino acid sequence and actual assignment of secondary structure. The packing...
The tertiary structure of a protein is formed by further winding and folding based on the secondary structure. It is mainly maintained by hydrophobic interactions between amino acid side chains, hydrogen bonds, and electrostatic interactions. Comparisons of predicted tertiary structures showed that the ...
In some instances, a short NIP-derived peptide fragment was found to be sufficient to induce necrosis and activate defense13,15,16. In other cases, disruption of the tertiary structure of the protein eliminated necrosis- and defense-inducing activities5,17. In search of novel NIPs, we have ...