So when one is setting out on a camping expedition, one reads up on the dangers that exist in the Aussie bush and, in doing so, is certain to encounter the term LD50. This, of course, is because Australia, the birthplace of the cuddly koala or the pattable wallaby, is also home to...
LCLo is closely related to the LC50 value which is the concentration which kills half of the test animals under controlled conditions.This value applies to vapors, dusts, mists and gases. Solids and liquids use the closely related LDLo value for routes other than inhalation....
The same observation applies to the definition of “organic,”“inorganic,”“element,”“organometallic,” etc. We have applied the “majority rule” (i.e., that the nature of the material is based on the component present in the greatest amount) to propose 1 single descriptor for each ...
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The results show that the long-term EE2 exposure affected, at both concentrations, reproductive parameters like the mRNA levels of hepatic vitellogenin and estrogen receptors. At the same concentrations, EE2 exposure modulated the immune parameters: mRNA levels of several immune genes were altered and...
Category 1 applies to corrosive substances, which can be further divided into three subcategories: category 1A, 1B and 1C, applied in the GHS and Packing Groups I, II and III applied in the UN Model Regulations for transport of dan- gerous goods. In the 21st revision of the Model ...
In brief, criterion 1 comprises compounds inducing acute (short-term) toxic effects in aquatic organisms (fish, crustacea and algae) in concentrations ≤ 1 mg/L (i.e. LC50/EC50 ≤ 1 mg/L). Criterion 2 comprises compounds inducing chronic (long-term) toxic effects in concentrations ≤ 0.1 ...
treatment in siRNAcircPVT1 and siRNAct transfected cells.iThe EC50 and the LD50 were determined using the Compusyn Software [58].CDDPcisplatin,EC50half maximum effective concentration;LC50half lethal concentration. Data are shown as mean of three replicates ± standard deviation (Student’s test...
Metabolomics is a new technology that applies advanced separation and detection methods to capture the collection of small molecules that characterize metabolic pathways. This rapidly developing discipline involves the study of the total repertoire of small molecules present in the biological samples, partic...
The Creative Commons Public Domain Dedication waiver (http://creativeco mmons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. Toussirot et al. Chem. Biol. Technol....