A muscular tube in the human male reproductive tract that carries sperm to the ejaculatory duct. Coronal sulcus The indented groove at the base of the human penis head. Rights and permissions Reprints and permissions About this article Cite this article Perlmutter, J.I., Bordenstein, S.R. Mic...
Targeting senescent cells enhances adipogenesis and metabolic function in old age. eLife 4, e12997 (2015). Article PubMed PubMed Central Google Scholar Bowman, K., Thambisetty, M., Kuchel, G. A., Ferrucci, L. & Melzer, D. Obesity and longer term risks of dementia in 65-74 year ...
4. Human internal exposure to NEOs 4.1. Levels of NEOs and metabolites in urine Due to quick metabolism and excretion of NEOs in human body, urinary NEOs mainly reflect short-term exposure. The half lives of IMI, CLO and DIN in humans were reported to be 1.45, 0.58 and 0.17 days, respe...
regulating the reproductive tissues and phenotype characteristics, can be progressively changed according to individual health history, encompassing life time accumulated environmental toxicants, pharmaceuticals, and age-reduced cardiovascular fitness. The monitoring of all those long-term effects is needed to...
Endometrial stem/progenitor cells are a type of stem cells with the ability to self-renew and differentiate into multiple cell types. They exist in the end
Circadian profiles were further dichotomized to be “Combined” when both the sinusoidal and linear terms were significant or only circadian (Circ. only) when the sinusoidal but not the linear term was significant in the Cosinor regression. c The box and whisker plots for amplitude estimates for...
(Figure 1). In this view, stem cells in both young and old adults alike are ultimately derived only from stem cells of fetal origin through their ability to sustain long-term self-renewal, and thus the ‘‘aging’’ of a stem cell lineage can be thought to commence upon definitive ...
Recent studies have shown that umbilical cord mesenchymal stem cells have an anti-aging effect in ovaries, but the cellular and molecular mechanisms of HA-MSC ovarian anti-aging remain to be studied. Therefore, we conducted a 10X Genomics single-nucleus
IIIs are especially important for antiviral defense at epithelial barrier surfaces [5], particularly in the lung [6], gut [7], and female reproductive tract [8], as well as in the human liver [9]. IFN-IIIs exert antiviral effects that are very similar to those of IFN-Is. Vertebrate ...
Numerous studies have used human pluripotent stem cell-derived cerebral organoids to elucidate the mystery of human brain development and model neurological diseases in vitro, but the potential for grafted organoid-based therapy in vivo remains unknown. Here, we optimized a culturing protocol capable ...