Eukaryotic gene transcription is often controlled at the level of RNA polymerase II (Pol II) pausing in the promoter-proximal region. Pausing Pol II limits the frequency of transcription initiation (‘pause-initiation limit’), predicting that the pause
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Inset: Schematic representation of the ELISA assay. n = 4. ***: P = 0.0006, **: P = 0.001 by one-way ANOVA and Dunnett´s multiple comparison test. Mean values ± SD. HRP: horseradish peroxidase. Full size image FXII_ΔPR-III interferes with platelet-driven ...
This overly simplified representation of the BC subcomplex in Arabidopsis plastids does not portray the range of oligomerization states, associations with other BADC and BCCP subunits, their intrinsic disorder, and the anticipated complexity of the mixtures of structural ensembles. With multiple BADC ...
We made several constructs to express an enzyme with a removable N-terminal tag in the presence or absence of the signal sequence and compared the kinetics parameters. The results reveal that the C-terminal tag is detrimental to enzyme activity, and that the presence of the signal sequence is...
Fig. 1. The three-dimensional structure of Mtb cPknF domain and active site. (A) Surface representation of the four molecules of the crystal asymmetric unit (chain A to D) organized in two dimers. The IKK16 inhibitor is shown as red spheres. (B) A single molecule of cPknF with the ...
Graphical representation of the statistics and detailed processed data is plotted within Figure 1. Figure 1. Quantification of A. muciniphila cells in BHI medium after a 72 h fermentation period. The culture medium was enriched with supplemental substrates, including FD β-glucan (FD), SD β-...
Figure 1. Schematic representation of methodology used to assess lethal and sublethal effect of Simarouba sp. aqueous extract against P. xylostella. The experiment for the bioactivity assay of AE-S on P. xylostella was a completely randomized design, with seven treatments (six concentrations and...
The parasitic mite, Varroa destructor, is the most serious pest of the western honey bee, Apis mellifera, and has caused the death of millions of colonies worldwide. This mite reproduces in brood cells and parasitizes immature and adult bees. We investig
(DEG) analysis was carried out using the DESeq2 package [21]. DEGs were identified using an adjusted p-value cutoff of 0.05. Gene ontology (GO) enrichment analyses were performed using PANTHER overrepresentation test, on the web-based tool offered by the Gene Ontology Consortium. Principal ...