胺作为一类非常有效的药物官能团,存在于大多数药物结构之上。本文总结现有胺的合成的主要方法,以及探索寻找新的胺的合成方法。 Amines, as a class of very effective drug functional groups, exist on most pharmaceutical struc-tures. In this paper, we summarize th
Angel A N M,Graham R.The synthesis of amines by the homo-geneous hydrogenation of secondary and primary amides. Chemical Communications . 2007Angel A N M, Graham R. The synthesis of amines by the homogeneous hydrogenation of secondary and primary amides [ J ]. Chemical Communications, 2007 (...
Synthesis of amines and intermediates for the synt 专利名称：Synthesis of amines and intermediates for the synthesis thereof 发明人：Ulrich Berens,Oliver Dosenbach,Daniel Sprenger 申请号：US13459290 申请日：20120430 公开号：US08710093B2 公开日：20140429 专利内容由知识产权出版社提供 摘要：Array 申请人：...
Synthesis of novel (phenylalkyl)amines for the investigation of structure-activity relationships. Part 1. Mescalin derivatives. Trachsel,Daniel. Helvetica ... D Trachsel - 《Cheminform》 被引量: 27发表: 2003年 Synthesis of novel (phenylalkyl)amines for the investigation of structure—activity relati...
Our current food system relies on unsustainable practices, which often fail to provide healthy diets to a growing population. Therefore, there is an urgent demand for new sustainable nutrition sources and processes. Microorganisms have gained attention a
Direct asymmetric reductive amination is one of the most efficient methods for the construction of chiral amines, in which the scope of the applicable amine coupling partners remains a significant challenge. In this study we describe primary alkyl amines
The overuse of antibiotics has led to lethal multi-antibiotic-resistant microorganisms around the globe, with restricted availability of novel antibiotics. Compared to conventional antibiotics, evolutionarily originated antimicrobial peptides (AMPs) are
The Curtius rearrangement and related reactions are often used to convert carboxylic acids to the corresponding primary amines. However, this reaction ofte... B Ma,WC Lee - 《Cheminform》 被引量: 16发表: 2010年 1,2,3-Thiadiazolyl Isocyanates in the Synthesis of Biologically Active Compounds. ...
The broad bioactivities of nonribosomal peptides rely on increasing structural diversity. Genome mining of the Burkholderiales strain Schlegelella brevitalea DSM 7029 leads to the identification of a class of dodecapeptides, glidonins, that feature diver
Amines, both primary and secondary amines, are important raw materials in the synthesis of bioactive molecules in pharmaceuticals synthesis. There are many methods developed and utilized in both industry and academia to obtain amines, such as amination of aryl halides or alcohols, reductive amination ...