Guided by gut sensory cues, humans and animals prefer nutritive sugars over non-caloric sweeteners, but how the gut steers such preferences remains unknown. In the intestine, neuropod cells synapse with vagal neurons to convey sugar stimuli to the brain within seconds. Here, we found that cholecy...
Although glucagon-like and insulin-like hormones have been found across animal phyla, incretin-like EEC-derived hormones have not yet been characterised in invertebrates. Here, we show that the midgut-derived hormone, neuropeptide F (NPF), acts as the sugar-responsive, incretin-like hormone in ...
Bawab W, Chastre E, Gespach C (1991) Functional and structural characterization of the secretin receptors in rat gastric glands: desensitization and glycoprotein nature. Biosci Rep 11:33–42 Article PubMed CAS Google Scholar Baxter GS, Clarke DE (1992) Benzimidazolone derivatives act as 5-HT...
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The management of inflammatory bowel diseases has been widely investigated, especially ulcerative colitis. Thus, studies with the application of new probiotic products are needed in the prevention/treatment of these clinical conditions. The objective of
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In particular, similar to drugs of abuse, microdialysis studies in animals revealed that the consumption of HPF (rich in sugar and/or fat), activating VTA dopaminergic neurons, triggers dopamine release in the NAc, which is correlated to their reinforcing properties [47], [48]. Ghrelin was ...
Sugars are thought to regulate both plant juvenile-to-adult and adult-to-reproductive phase transitions through their function as key signaling molecules and energy sources. Most plant cells acquire their essential carbon from sucrose; however, this sugar is not utilized directly. Cytosolic invertase ...
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