Cell surface structures of the bacterium could be implicated in pathogenesis. Here we report the following structure of the lipopolysaccharide O-chain of F.nucleatum strain 12230: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- where ABu and HBu indicate (R)-3-aminobutanoyl and ...
Structure 1 in CE358 LPS lacks the galacturonosyl residue. Glycosyl linkage and tandem mass spectrometry analyses show that the intact LPS core region consists of trisaccharide (2) attached to O-4 of the Kdo residue in tetrasaccharide 1, and that an additional Kdo residue is attached to O-...
The private equity fund’s partners are known as general partners. Under the structure of each fund, GPs are given the right to manage the private equity fund and pick which investments they will include in their portfolios. GPs are also responsible for attaining capital commitments from investors...
Vinogradov, E, Petersen, BO, Duus, JØ, Radziejewska-Lebrecht, J (2003) The structure of the polysaccharide part of the LPS from Serratia marcescens serotype O19, including linkage region to the core and the residue at the non-reducing end. Carbohydr Res 338: pp. 2757-2761...
YU102 improves cognitive function in an LPS-induced mouse model of neuroinflammation To determine the effects of proteasome inhibitors (PIs) including iP-selective inhibitors on cognitive function, we chose to use a lipopolysaccharide (LPS)-induced mouse model of neuroinflammation, known to display AD...
A mode of diffusion in which molecules diffuse freely in the membrane except when they encounter a barrier (such as a structure (or structures) associated with actin filaments), the crossing of which hinders diffusion. Interferometric scattering microscopy (iSCAT). A microscopy technique to enhance...
We have used a combination of chemical, analytical and NMR spectroscopy approaches to define the complete structure of the core oligosaccharide from A. pasteurianus CIP103108 LPS. Interestingly, the core oligosaccharide displays a high concentration of negatively charged groups, structural features that ...
Ionic Binding of 3H-Gentamicin and Short-Term Bactericidal Activity of Gentamicin against Pseudomonas aeruginosa Isolates Differing in Lipopolys... The clinical isolates of Pseudomonas aeruginosa can be roughly classified into long-and short-lipopolysaccharide (LPS) strains and LPS-deficient strains, b.....
Since the pronounced increase of the toxic metabolites such as Kyn and Quin induced by CRS in the mouse colon, then the colonic structure integrity of the mice in this study was evaluated using their histological scores (Fig. 7A, B). CRS was found to cause evident epithelial structure ...
However, the effect was not species-specific, suggesting that a conserved portion of the lipid A may be the responsible component of the LPS structure (3). In later stages of the colonization process, bacterial peptidoglycan acts synergistically with LPS to induce most, if not all, of light ...