IV.—THE STRUCTURE OF THE CHROMOSOME.*First page of articledoi:10.1111/j.1365-2818.1938.tb00831.xR. Ruggles GatesJohn Wiley & Sons, LtdJournal of Microscopy
centromere from chromosome 8 in chimpanzee, orangutan and macaque to reconstruct its evolutionary history. Comparative and phylogenetic analyses show that the higher-order α-satellite structure evolved in the great ape ancestor with a layered symmetry, in which more ancient higher-order repeats locate ...
2. A photomicrograph of chromosomes arranged according to a standard classification. tr.v. kar·y·o·typed, kar·y·o·typ·ing, kar·y·o·types To classify and array (the chromosome complement of an organism or a species) according to the arrangement, number, size, shape, or other ...
Nse2 is a subunit of the Smc5/6 complex that possesses SUMO E3 ligase activity by the presence of a SP-RING domain that activates the E2~SUMO thioester for discharge on the substrate. Here we present the crystal structure of the SUMO E3 ligase Nse2 in complex with an E2-SUMO thioester...
Mouse chromosome behaviour has been studied in the anaphase, after the cells (culture L) were incubated with fluorochrome Hoechst 33258, provoking the stretching of the chromosome centromeric regions. It was shown that in spite of marked structural changes in the centromere, the cells entered the ...
A structure in all living cells that carries the genes that determine heredity. In all cells except bacterial cells, the chromosomes are thread-like strands of DNA and protein that are contained in the nucleus. They occur in pairs in all of the cells of eukaryotes except the reproductive cells...
The structure of a repeated DNA sequence located on the short arm of the human Y chromosome is described. Genomic mapping and cloning in lambda or cosmid vectors show that the repeated sequence consists of units 20·3 × 10 3 base-pairs long that contain the three previously described DNA se...
A comparison of the structure of a T=3 virus with those of poliovirus and of cowpea mosaic virus is shown in Fig. 2.7. Poliovirus has 60 copies of each of three different proteins, whereas the comovirus has 60 copies of an L protein (each of which fills the niche of two units) and...
We sought to investigate in depth the chromatin structure of chromosome region 11p15.5 and its potential deregulation in the related imprinting diseases (BWS and SRS), focusing particularly oncisregulatory elements, including enhancers and CTCF-binding sites. To achieve this aim, we have chosen the ...
Centromeres are chromosome regions crucial for sister chromatid attachment, while centrosomes are cell organelles that organize microtubules.