mitochondria genomemolecular identificationChrysomya phaonis (Seguy, 1928) is one of the blowflies of great medical and forensic importance. In this paper, we report that the entire genome of mitochondrial DNA o
The mitochondria are also known as the "powerhouse" of the cell. Their main function is to complete aerobic respiration producing ATP. It does this by oxidizing NADH and FADH2 within the electron transport chain. This is located along the inner mitochondrial membrane and is responsible for the ...
given that mitochondrial DNA (mtDNA) is dwarfed by the size of the nuclear genome (nDNA), nuclear genetics has represented a focal point in cancer biology, often at the expense of mtDNA and mitochondria. However, genomic sequencing and advances in in vivo models underscore the importance ...
Febs LettersFonyo, A, Ligeti, E (1978) Intramitochondrial phosphate is the source of protons in the response of liver mitochondria to cations. FEBS Lett 96: pp. 343-345Fonyo A, Ligeti E (1978) Intramitochondrial phosphate is the source of protons in the response of liver mitochondria to ...
As such, mitochondria have a fundamental role in the neurodegenerative process of Parkinson’s disease (PD), the most common neurodegenerative movement disorder in the world. PD affects about 1% of people over the age of 60 years (de Lau and Breteler, 2006; Mehta et al., 2007) and is ...
microns. Mitochondria are said to be the “power houses” of the cell because many of the chemical changes associated with respiration take place in these structures. As glucose is broken down in respiration, energy is released. This energy goesi nto the manufacture ofATP(adenosine triphosphate)...
et al. The functional role of TLR9 in human platelets. Blood 118, 366 (2011). Google Scholar Boudreau, L. H. et al. Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation. Blood 124, 2173–2183 (2014). CAS PubMed ...
The induction of mitochondria-mediated apoptosis in cancer cells by ruthenium(II) asymmetric complexes Four ruthenium(ii) asymmetric complexes, [Ru(bpy)2(PAIDH)]2+(bpy = 2,2鈥 -bipyridine, PAIDH = 2-pyridyl-1H-anthra[1,2-d]imidazole-6,11-dione,1), [Ru(phen)2(... Q Chen,JQ Wang...
In the present study we used the specific inhibitors of Trx2 and GSH antioxidant systems auranofin and DNCB as well as the catalase inhibitor aminotriazole to evaluate the relative contribution of the individual systems to hydrogen peroxide detoxification in rat brain mitochondria, rat hippocampal ...
Gene duplication, re-targeting of proteins to and from mitochondria, secondary gene loss and lateral gene transfer (LGT) have all played important roles in generating this diversity in mitochondria, although the relative importance of these mechanisms is debated 20, 21, 22, 23. Here we review ...