MAF文件通常包含多个样本的突变信息,例如SNP和INDEL,以及这些突变的注释信息。 MAF文件通常用于描述肿瘤样本中的突变信息,但也可以用于其他类型的样本。 MAF文件通常包含多个样本的突变信息,例如SNP和INDEL,以及这些突变的注释信息。 MAF文件中的每一行都描述了一个变异,并且包含多个参数,例如变异的位置、变异的类型、...
To analyse the joint genetic architecture of poverty, we ran a multivariable GWAS for which a common factor defined by genetic indicators is regressed on a single nucleotide polymorphism (SNP). The multivariable GWAS of the latent poverty factor (PF) was modelled from three indicators: HI, SD ...
Lung cancer is the leading cause of cancer-associated mortality worldwide1. Here we analysed 1,644 tumour regions sampled at surgery or during follow-up from the first 421 patients with non-small cell lung cancer prospectively enrolled into the TRACERx s
According to the half r2 value of the six breeds, we considered 10 kb as the SNP site-linked distance for the signal detection window. Genome-wide selective signature detection To better mine the functional areas closely related to egg-laying traits, we assigned three breeds (HY, ZE, SC, ...
The evolution of modern human populations has been accompanied by dramatic changes in environment and lifestyle [1]. Positive selection, the driving force behind adaptive evolution, is the process whereby a genetic variant rapidly increases in frequency in a population due to the fitness advantage of...
The frequency of tags matching once the genome sequence but not in an annotated exon suggests that the human transcriptome is much more complex than shown by the current human genome annotations, with many new splicing variants and antisense transcripts. SAGE data is appropriate to map new ...
Currently, six commercial whole-genome SNP chips are available for cattle genotyping, produced by two different genotyping platforms. Technical issues need to be addressed to combine data that originates from the different platforms, or different version
Please check the relevantusage guidelineswhen using these services. Note that Entrez server requests are subject to frequency limits. Consider obtaining an NCBI API key if are a heavy user of E-utilities. Installation You can install the released version of reutils fromCRANwith: ...
The Fourier transform takes us from thetimeto thefrequencydomain, and this turns out to have a massive number of applications.Thefast Fourier transform(FFT) is an algorithm for computing the DFT; it achieves its high speed by storing and reusing results of computations as it progresses. ...
Chenopodium quinoa (quinoa) is a highly nutritious grain identified as an important crop to improve world food security. Unfortunately, few resources are available to facilitate its genetic improvement. Here we report the assembly of a high-quality, chro