The sequence of the human genome. Venter JC,Adams MD,Myers EW,et al. Science . 2001Venter JC, Adams MD, Myers EW et al (2001) The sequence of the human genome. Science 291, 1304- 1351Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG, et al. The sequence of the ...
The Sequence of the Human Genome J. Craig Venter, 1 * Mark D. Adams, 1 Eugene W. Myers, 1 Peter W. Li, 1 Richard J. Mural, 1 Granger G. Sutton, 1 Hamilton O. Smith, 1 Mark Yandell, 1 Cheryl A. Evans, 1 Robert A. Holt, ...
阅读理解The Human Genome Project(人类基因组计划was an international research effort to determine thesequence(序列) of the human genome and identify thegenes that it contains. The Project was led by theNational Institutes of Health and the U. S. Departmentof Energy. Additional contributors included...
Human Genome Project n. An international scientific research project that was conducted between 1990 and 2003 to determine the base-pair sequences in human DNA and to store this information in computer databases for the subsequent identification and analysis of genes and other features of the genome...
The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and make freely available a draft sequence of the human genome. We also present an initial analysis of the...
The human X chromosome has a unique biology that was shaped by its evolution as the sex chromosome shared by males and females. We have determined 99.3% of the euchromatic sequence of the X chromosome. Our analysis illustrates the autosomal origin of the
What if, I said, some philanthropic source descended into our midst and offered $3 billion to produce the sequence of the human genome at the end of 10 years? And, I suggested, assume that we were assured that there would be no impact on existing sources of funding. Would the project ...
Inherited genetic variation has a critical but as yet largely uncharacterized role in human disease. Here we report a public database of common variation in the human genome: more than one million single nucleotide polymorphisms (SNPs) for which accurate and complete genotypes have been obtained in...
aSequences of the entire human genome reveal a relative richness in structure with repetitive elements, tandem repeats, inverted repeats, and palindrome structures. Focusing on structure, the evolution of X and Y chromosomes in primates is reviewed here, and the relationship between gene expression ...
The main disappointment is that at present, 16 years after the sequence of the first human genome was announced, no major breakthrough in the prevention or treatment of disease has resulted from DNA sequence data. One problem is that interpreting the meaning of DNA sequence data has been more...