The science of genetics was, however, born only in this century largely because of the failure of earlier workers to separate continuous from discontinuous variation in their thought and work. Progress in our u
Role of genes and environments for explaining Alzheimer disease. Arch. Gen. Psychiatry 63, 168–174 (2006). Article PubMed Google Scholar Zdravkovic, S. et al. Heritability of death from coronary heart disease: a 36-year follow-up of 20 966 Swedish twins. J. Intern. Med. 252, 247–...
In the past five years, nuclear DNA mutations have been found in genes that affect several aspects of OXPHOS function: structural OXPHOS genes, intergenomic communication, OXPHOS-complex assembly, import and energy homeostasis. Progress in this field has greatly benefited from the human genome proje...
Figure 5.1: Homozygous and heterozygous inheritance Interestingly, many traits that are supposedly one-gene, ormonogenic, traits (like eye color or the curvature of your thumb) are not. Instead, they arepolygenic, controlled by multiple genes. ...
Poultry Science Volume 102, Issue 6, June 2023, 102657Genetics and Molecular BiologyThe study of selection signature and its applications on identification of candidate genes using whole genome sequencing data in chicken—a review Author links open overlay panelSemiu Folaniyi Bello * † ‡, ...
Under the leadership of James Watson, it was decided to focus the first 5 years of the HGP on the development of genetic and physical maps of the human genome, which would themselves be of great value to scientists hunting for disease genes. The HGP also tackled mapping and sequencing of ...
understanding the genetic architecture and accurately quantifying inbreeding and inbreeding depression require a genome-wide perspective, encompassing for example the number of genes involved, the presence of alleles with large effects, the role of deleterious recessive alleles, and heterozygote advantage [9...
and using a genome-wide association study, we identify genes responsible for Tartary buckwheat domestication and differentiation, which we then experimentally validate. Comparative genomics and QTL analysis further shed light on the genetic foundation of the easily dehulled trait in a particular variety ...
Hereditary effects on division of labour are more pervasive than previously supposed. The genes that underlie hereditary effects on division of labour have yet to be identified. Hereditary effects on division of labour raise the spectre of conflict between those that are reproducing and those that ar...
The properties of the human Y chromosome – namely, male specificity, haploidy and escape from crossing over — make it an unusual component of the genome, and have led to its genetic variation becoming a key part of studies of human evolution, population history, genealogy, forensics and male...