Epigenetics: the science of change.(Environews: Focus) B Weinhold 被引量: 0发表: 0年 Rapid DNA methylation changes after exposure to traffic particles. We estimated standardized regression coefficients (beta) expressing the fraction of a standard deviation change in DNA methylation associated with a...
Here, we describe the importance of including epigenetics in genetic and environmental epidemiology studies, provide a conceptual framework when considering epigenetic data in population-based studies and touch upon the many challenges that lie ahead. 展开 关键词: environmental epidemiology epidemiology ...
Investigator of the Howard Hughes Medical Institute. Dr. Zhang is an internationally renowned scientist in epigenetics. Over the last decade, he has made significant contributions to the epigenetic
NSR 自己的说法是,她是中国第一本英文的综合性科学综述杂志。 但是现在,在官网首页上的描述是: National Science Review is an open access, peer-reviewed journal aimed at reporting cutting-edge developments across science and technology in China and around the world. The journal covers all areas of the...
Since its discovery in 1983, the epigenetics of human cancer has been in the shadows of human cancer genetics. But this area has become increasingly visible with a growing understanding of specific epigenetic mechanisms and their role in cancer, including hypomethylation, hypermethylation, loss of imp...
Science 339, 1567–1570 (2013). CAS PubMed Google Scholar Easwaran, H., Tsai, H. C. & Baylin, S. B. Cancer epigenetics: tumor heterogeneity, plasticity of stem-like states, and drug resistance. Mol. Cell 54, 716–727 (2014). CAS PubMed PubMed Central Google Scholar Kulis, M. ...
This updated overview of the ChIP procedure includes additional detail about primary antibody selection (i.e., ChIP-validated antibodies). The application note also describes and provides examples of ChIP as a technique for studying epigene...
aspects of medical epigenetics. It is useful not only to physicians, nurses, medical students, and many others directly involved with healthcare, but also investigators in life sciences, biotech companies, graduate students, and all others who are interested in more applied aspects of epigenetics. ...
Abnormal penile foreskin development in hypospadias is the most frequent genital malformation in male children, which has increased dramatically in recent decades. A number of environmental factors have been shown to be associated with hypospadias develo
注释:表观遗传学(Epigenetics)是与遗传学(Genetics)相对应的概念。遗传学是指基于基因序列改变所致基因表达水平变化,而表观遗传学则是指基于非基因序列改变所致基因表达水平变化。 IV This picture depicts the difference between the two categories of scientists, the Scientists of What being featured by the colle...