The role of RNA and protein synthesis in differentiating spores of the fungusPhytophthora palmivora was investigated using inhibitors, precursor assimilation, andin vitro translation of directly extracted RNA.
enzymes may pave the way for novel RNA-based therapies, enabling tailored interventions for specific cancer subtypes. This review provides a comprehensive overview of the roles and mechanisms of various coding and noncoding RNA modifications in cancer progression and highlights recent advancements in RNA...
Regulatory RNA is emerging as the major architect of cognitive evolution and innovation in the mammalian brain. While the protein machinery has remained largely constant throughout animal evolution, the non protein-coding transcriptome has expanded considerably to provide essential and widespread cellular ...
transported through monocarboxylate transporter protein 4. This transport mechanism contributes to the creation of an acidic microenvironment within cancer cells, ultimately leading to the polarization of M2 macrophages and the promotion of immunosuppressive function in Treg cells [3]; Conversely, it inhibi...
It has been suggested that the heterogeneous groups present in the circRNAs are the contributory factors in the development of different human disorders and their probable roles in gene regulation [1]. The arising function of circRNAs acting as microRNA (miRNA) sponge has been greatly discussed in...
Learn about the key steps in preparation of DNA sequencing library for Illumina systems. This section covers DNA sequencing methods, fragmentation strategies, end conversion, adapter ligation, library amplification, size selection, and lib...
Extraction of DNA, RNA, and protein is the basic method used in molecular biology. These biomolecules can be isolated from any biological material for subsequent downstream processes, analytical, or ...
Roles are emerging for small RNAs in DNA repair and genome maintenance, through both the maintenance and regulation of heterochromatic domains (such as centromeres and telomeres) and through direct involvement in DNA repair: for example, at double-strand breaks. ...
Since their discovery, they have been found to play crucial roles in many physiological and pathological processes, and the last 10 years have witnessed the explosion of studies on exosomes and other EVs. They carry large amounts of materials, including proteins, lipids, and miRNA/mRNA/DNA, ...
Structure of the gene 2.5 protein, a single-stranded DNA binding protein encoded by bacteriophage T7 The gene 2.5 protein (gp2.5) of bacteriophage T7 is a single-stranded DNA (ssDNA) binding protein that has essential roles in DNA replication and recombina... T Hollis,JM Stattel,DS Walther...