Rous, P. The possible role of viruses in cancer. Opening remarks. Cancer Res. 20, 672–676 (1960). CAS PubMed Google Scholar Temin, H. M. & Rubin, H. Characteristics of an assay for Rous sarcoma virus and Rous sarcoma cells in tissue culture. Virology 6, 669–688 (1958). Article...
Cancer immunotherapy has rapidly transformed cancer treatment, yet resistance remains a significant hurdle, limiting its efficacy in many patients. Circular RNAs (circRNAs), a novel class of non-coding RNAs, have emerged as pivotal regulators of gene exp
Cell migration, a hallmark of cancer malignancy, plays a critical role in cancers. Improperly initiated or misdirected cell migration can lead to invasive metastatic cancer. Migrasomes are newly discovered vesicular cellular organelles produced by migrating cells and depending on cell migration. Four mar...
There are examples of viruses which cause cancer by carrying an activated oncogene into a cell. However, no cancer-causing viruses have been found that carry tumor suppressor genes. Why is this? Explain how viruses such as HPV and the hepatitis virus can cause cancers. Differentiate between vi...
effects of viral infection on the development of CSCs and the suppression of CSCs by OV therapy were examined in this paper. The purpose of this review is to investigate the dual role of viruses in CSCs (oncolytic virotherapy and viral oncogenes)....
Since the late 1990s, infectious agents have been thought to play a role in the pathogenesis of approximately 15% of cancers. It is now widely accepted that infection of stomach tissue with the bacteria Helicobacter pylori is an important cause of stomach adenocarcinoma. In addition, oncogenic vi...
Syndrome coronavirus-2 (SARS-CoV-2) has developed various strategies to evade the antiviral impact of type I IFN. Non-structural proteins and auxiliary proteins have been extensively researched on their role in immune escape. Nevertheless, the detailed mechanisms of structural protein-induced immune ...
Cancers with the largest proportions (>60%) attributable to these risks were cervix uteri cancer, lung cancer, and oesphagus cancer. The main risk factors for these cancers included sexual transmission of HPV leading to persistent infection with oncogenic viruses, smoking, alcohol use, and low fr...
tumor cells and cells in the tumor microenvironment of various cancers. In particular, TLR3, TLR4, TLR5 and TLR9 are frequently found in cervical cancer tissues.7–10Furthermore, the activation of TLRs by different ligands plays important role in the development and progression of cervical cancer...
the role of IFITMs and SARS-CoV-2 infection. While IFITMs have widely been demonstrated to inhibit infection, in hCoV, OC43, IFITM2, and IFITM3 have been shown to increase viral entry into cells [68, 69]. Alternatively, in SARS-CoV-2 infections, early in vitro studies demonstrated ...