The Role of the Mitochondria in the Evolution of Stem Cells, Including MUSE Stem Cells and Their BiologyWARBURG hypothesisHuman adult stem cellsGap junctional intercellular communicationOxidative stressFrom the transition of single-cell organisms to multicellularity of metazoans, evolutionary pressures ...
答案:Mitochondria are often referred to as the "powerhouses" of the cell because they generate most of the cell's supply of adenosine triphosphate (ATP), which is used as a source of chemical energy. They are unique among cellular organelles because they have their own mitochondrial DNA and ...
Virtually every aspect of mitochondrial research and medicine is addressed in this volume, including mitochondrial function and dysfunction, free radical biology relevant to mitochondrial dysfunction, the role of mitochondria in apoptosis, and abnormal signaling processes and disease mechanisms associated with...
Recent studies have implicated mitochondrial dysfunction as a trigger of inflammatory bowel diseases, including Crohn’s disease (CD) and ulcerative colitis (UC). We have investigated the role of the mitochondria gate-keeper protein, the voltage-dependent-anion channel 1 (VDAC1), in gastrointestinal...
(IL1) through the formation and activation of the inflammasome, a large protein complex, at the interface of the mitochondria and the ER. This indicates that MERCs play a role in the development of the innate immune response36,37,38,39,40. Together, this leads to a state of inflammation ...
The role of mitochondria in the pathophysiology of skeletal muscle insulin resistance. Endocr. Rev. 31, 25–51 (2010). Article CAS PubMed Google Scholar Chance, B. et al. Control of oxidative metabolism and oxygen delivery in human skeletal muscle: a steady-state analysis of the work/...
What is the role of the mitochondrion?Mitochondria:Eukaryotic cells contain many membrane-bound organelles; one such organelle is the mitochondrion. It is essential to the survival of the cell. One cell can contain multiple mitochondria.Answer and Explanation: ...
theroleofmitochondriainmtor-regulatedlongevity 系统标签: mtormitochondrialongevityregulatedmitochondrialrole Biol.Rev.(2015),90,pp.167–181.167 doi:10.1111/brv.12103 TheroleofmitochondriainmTOR-regulated longevity YuehuaWei ∗ ,Yan-JieZhang,YingCaiandMang-HuaXu No.3People’sHospital,SchoolofMedicine,Shang...
Mitochondria are implicated in several metabolic pathways including cell respiratory processes, apoptosis, and free radical production. Mitochondrial abnor
The possible participation of mitochondria-rich cells in transepithelial Na + transport across frog skin under "physiological conditions" (low apical [Na + ], open circuited) was analysed by recording electrophysiological parameters from principal cells with intracellular microelectrodes and using measurement...