"Senescent cells can occupy niches with privileged positions as 'sentinels' that monitor tissue for injury and respond by stimulating nearby stem cells to grow and initiate repair," said Tien Peng, MD, associate professor of pulmonary, critical care, allergy and sleep medicine, and senior author ...
Introduction Functions of skin-resident adult stem/progenitor cells in skin regeneration Altered functions of skin-resident adult stem/progenitor cells dur... M Mimeault,SK Batra - 《Journal of Cellular & Molecular Medicine》 被引量: 55发表: 2010年 Role of Age-Associated Alterations of the Dermal...
Although the pathogenesis of essential hypertension is not clear, a large number of studies have shown that oxidative stress plays an important role in the occurrence and development of hypertension and target organ damage. This paper systematically summ
Mutations that drive accelerated ageing in prototypical progeria syndromes in humans point to an important role for genome maintenance and stability. Together, these different strands of genetic research are highlighting pathways for the discovery of anti-ageing interventions that may be applicable in ...
Aging is an irreversible and natural phenomenon that occurs as a person ages. Anti-aging medicine applies advanced science and medical technology to early detection, prevention, treatment, and reversal of age-related dysfunctions, disorders, and diseases. Therefore, anti-aging diagnostic medicine and ...
The mitochondrion has an indispensable role in the development and function of immune cells, from energy supply to the activation, proliferation, and phagocytosis, and ending with repairs and regeneration. Besides energy supply, with the help of mitochondrial reactive oxygen species (ROS), the immune...
Adipose tissues in the hypodermis, the crucial stem cell reservoir in the skin and the endocrine organ for the maintenance of skin homeostasis undergo significant changes during skin aging. Dermal white adipose tissue (dWAT) has recently been recognized
Patient guide to stem cell therapies For better or worse, I am in the unique position of being a stem cell scientist and also a former cancer patient. This does give me a unique perspective on things. Neural stem cells. Keep in mind this is not medical advice and you should absolutely ...
Abnormal penile foreskin development in hypospadias is the most frequent genital malformation in male children, which has increased dramatically in recent decades. A number of environmental factors have been shown to be associated with hypospadias development. The current study investigated the role of ep...
In the last few decades, the role of cancer stem cells in initiating tumors, metastasis, invasion, and resistance to therapies has been recognized as a potential target for tumor therapy. Understanding the mechanisms by which CSCs contribute to cancer progression can help to provide novel therapeuti...