The role of Hsp70 inoxi-inflamm-aging and its use as a potential biomarkerof lifespan. de Toda IM,Dela Fuente M. Biogerontology . 2015de Toda IM, De la Fuente M (2015) The role of Hsp70 in oxi-inflamm-aging and its use as a potential biomarker of lifespan. Biogerontology 16:709–...
Franceschi C, Olivieri F, Marchegiani F et al (2005) Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians. Mech Ageing Dev 126:351–361 Article CAS PubMed Google...
also play a positive role in wound healing and tumor inhibition.13The determinant that matters favorable or lousy cell senescence largely relies on the duration: long-term type of cell senescence is prone to inflammation and disease, while short-term type sometimes seems beneficial because the immu...
elegans: is the oxidative damage theory of aging wrong? Cell Cycle 8, 1681–1687 (2009). Article CAS PubMed Google Scholar De la Fuente, M. & Miquel, J. An update of the oxidation-inflammation theory of aging: the involvement of the immune system in oxi-inflamm-aging. Curr. Pharm. ...
An Update of the Oxidation-Inflammation Theory of Aging: The Involvement of the Immune System in Oxi-Inflamm-Agingdoi:10.2174/138161209789058110ingentaconnectCpdFuenteMonicaMiquelJaimeDe la Fuente M,Miquel J.An update of the oxidation-inflammation theory of aging:the involvement of the immune system ...
also been observed in hippocampus of mice subjected to early social isolation stress [115]. In femalerhesus macaques, social interactions have been shown to influence mitochondrial DNA copy number inimmune cells[116]. The exact mechanisms how mitochondrial ROS participate in social isolation-induced pa...
The immune-mediating, antioxidant and antimicrobial roles of vitamins A to E were explored and their potential role in the fight against COVID-19 was evaluated. The major topics extracted for narrative synthesis were physiological and immunological roles of each vitamin, their role in...
4. Role of Nrf2 in NCDs 5. Interaction between Que and Nrf2 6. Potential therapeutic action of Que against NCDs through the Nrf2 pathway 7. Availability, pharmacokinetics, pharmaceutics, and clinical studies on Que 8. Conclusions and future prospects CRediT author statement Declaration of competing...
of longevity. Moreover, we have proposed the oxidation-inflammation theory of ageing, in which the immune system is involved in the rate of oxi-inflamm-ageing of the organism and in the biological age. This has been confirmed that applying several lifestyle strategies improves the immune cell...
Age-related changes in the immune system associated with aging play an essential role in the pathogenesis of kidney diseases. Consequently, it is essential to understand the interactions between immunosenescence and renal disorders. Numerous investigations of the underlying processes of age-related alterati...