Gestation, parturition, steroid hormones, and prostaglandins modulate both the generation and the effects of NO on the uterus. The changes in NO and its effects are consistent with the theory that NO plays a rol
Experimental data in both animals and humans indicate that maternal inflammation may disproportionately impact the viability of male conceptuses; however, it is unknown whether other factors associated with both pregnancy and inflammation, such as vitamin D status, are associated with the offspring sex ...
2, 3, 4 Among these regulatory hormones, FSH is unquestionably the most critical because it plays an indispensable role in maintaining the survival and growth of early antral follicles. FSH plays a role in exponential growth of ovarian follicles through facilitating the proliferation of granulosa ...
hormonal status, several models have been proposed to examine the role of sex hormones in gastrointestinal (GI) function including differences in GI symptoms expression in distinct phases of the menstrual cycle, in pre- and post-menopausal women, during pregnancy, hormonal treatment or after oop...
Inflammasomes are large protein complexes that play a major role in sensing inflammatory signals and triggering the innate immune response. Each inflammasome complex has three major components: an upstream sensor molecule that is connected to a downstrea
Sex hormones play a pivotal role as endocrine hormones that exert profound effects on the biological characteristics and vascular function of vascular smooth muscle cells (VSMCs). By modulating intracellular signaling pathways, activating nuclear recepto
‘Alpha Fucks’ side of Hypergamy. This can be attributed to a girl / young woman’s provisioning needs being relatively accommodated for by family, the state in some effect, or even her own self-provisioning, as well as the breeding urgency that comes with puberty, hormones and youth ...
It is widely held that the immune system evolved for maintaining the health of an individual. Health promotion is achieved through the ability of immune competent T-cells to recognize pathogens and respond to them, in a manner causing elimination of the pathogens. However, since immune responses...
In addition to soluble proteins and other hormones, cells shed membrane vesicles into the extracellular environment. These extruded vesicles have been shown to contain various signaling proteins and microRNAs, and their contents can be transferred to neighboring cells, resulting in changes in proliferative...
Inflammatory Bowel Disease (IBD), a chronic nonspecific intestinal inflammatory disease, is comprised of Ulcerative Colitis (UC) and Crohn’s Disease (CD). IBD is closely related to a systemic inflammatory reaction and affects the progression of many int