The role of T helper 25?cells in the immune response to Mycobacterium lepraeingentaconnectJOURNAL- AMERICAN ACADEMY OF DERMATOLOGYdeSousaJorgeRodriguesQuaresmaJuarezAntonioSim?es
T helper 17 (Th17) cells were first described as a novel T helper cell lineage independent from Th1 and Th2 subsets. Th17 cells play vital roles in inflammation and tumor immunity. It causes the dissipation of antitumor immunity and contribution to the survival of tumor cells, worsening tumor...
IMMUNOREGULATION BY INTERLEUKIN-12 477 The role of IL12 in helper T-cell differentiation V.L. Perez ('), J.A. Lederer c2), E. Camiel cl), A. Lichtman (l) and A.K. Abbas (l) (I) Immunology Research Division, Department of Pathology, Brigham & Women's Hospital and Harvard Medical...
Age-related T cell dysfunction can lead to failure of immune tolerance mechanisms, resulting in aberrant T cell-driven cytokine and cytotoxic responses that ultimately cause tissue damage. In this Review, we discuss the role of T cells in the onset and progression of age-associated conditions, fo...
The helper T cells are a group of white blood cells essential in mediating immune functions. Their primary role is to produce factors that activate...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can answer your tough ...
Objective: To explore the role of maternal periimplantation endometrial T-helper–1 (TH-1) and T-helper–2 (TH-2) cytokines in the success or failure of human reproduction and their relation to the endocrine system and subsequent pregnancy outcome. Design: Controlled, prospective study. Setting...
Follicular helper T cells may play an important role in the severity of primary Sjgren's syndrome The aim of this study was to investigate the possible role of follicular helper T (T-FH) cells in the pathogenesis of primary Sjogren's syndrome (pSS) by a... K Szabo,G Papp,S Barath,...
T cell response, the potential role of CD4+‘helper’ T cells has largely remained in the background. In this review, we give an overview of the multifaceted role of CD4+T cells in the anti-tumour immune response, with an emphasis on recent evidence that CD4+T cells play a bigger role...
Evidence suggests that PKCλ/ι par- ticipates in a variety of physiological and pathological processes, including the regulation of metabolism, growth, proliferation and differentiation of cells. However, the role of PKCλ/ι in liver disease caused by Schistosoma japonicum remains unclear. Methods...
Investigations of the role of MHC gene products in the antigen-mediated interaction of T cells with B cells or macrophages (MΦ) can be interpreted similarly. We present here evidence that in the mouse, helper T cells primed with the antigen, keyhole limpet haemocyanin (KLH), bound to the...