This chapter discusses the regulation of the cell cycle by somatomedins. The chapter analyzes a group of growth factors that resemble insulin鈥攊nsulin-like growth factors (ILGFs). The group consists of somatomedins A, nonsuppressible insulinlike activity (that is made up of insulin growth ...
细胞周期调控定 Regulation of the cell cycle.ppt,cyclinB ↓ APC 降解 ↓ MPF解聚、失活 组蛋白去磷酸化 ↓ 染色体去凝集 核纤层蛋白去磷酸化 ↓ 核膜组装 核形成 肌球蛋白去磷酸化 ↓ 收缩环溢缩、分裂沟加深 胞质分裂 MPF在细胞退出M期中的作用 检测点(checkpoint):
一、細胞分裂扮演之角色(Thekeyrolesofcelldivision)：1.在進行細胞週期(cellcycle)時，有絲分裂之中間要有間期(interphase)交互參雜其中，以利細胞分裂前各項之準備。CH4細胞週期(TheCellCycle)一、細胞分裂扮演之角色(Thekeyrolesofcelldivision)：1)細胞週期各階段之變化概述：a.細胞週期是由有絲分裂(含細胞質分裂...
Regulation of the meiotic cell cycle in oocytes. The mitotic and meiotic cell cycle share many regulators, but there are also important differences between the two processes. The meiotic maturation of Xen... AR Nebreda,I Ferby - 《Current Opinion in Cell Biology》 被引量: 618发表: 2000年 ...
Early passage murine fibroblasts infected with retroviral vectors carrying human c-myc 'minigenes' express high levels of c-myc and have a dramatically shortened G1-phase of the cell cycle. Cells infected with viruses where c-myc is expressed from the viral LTR (MSN-4 virus) express more c...
Detection of human papillomavirus and relevant tumor suppressors and oncoproteins in laryngeal tumors. Clin Cancer Res 2006; 12:6946–6951. Article CAS PubMed Google Scholar Carleton M, Cleary MA, Linsley PS . MicroRNAs and cell cycle regulation. Cell Cycle 2007; 6:2127–2132. Article CAS ...
The biology, structure and regulation of DUBs have been extensively reviewed elsewhere, so here we focus specifically on roles of DUBs in regulating cell cycle processes in mammalian cells. Over a quarter of all DUBs, representing four different families, have been shown to play roles either in ...
A MATHEMATICAL MODEL FOR THE Glk.3 TRANSITION OF THE MAMMALIAN CELL CYCLE The model simulates the qualitative consequences on cell cycle regulation of overexpression of cyclin E, E2F, and of RB deregulation in agreement with experiment. Bifurcation analysis of the model suggests strategies for ration...
The control of metazoan cell proliferation, a problem long the domain of cell culture studies, is now being examined in developing animals. Surprisingly, developmental regulation is mediated at a variety of cell-cycle stages. Highly conserved cell-cycle control mechanisms provide a focus for studying...
Regulation of cell cycle-specific gene expression in fission yeast by the Cdc14p-like phosphatase Clp1p. Regulation of cell cycle-specific gene expression in fission yeast by the Cdc14p-like phosphatase Clp1p. J Cell Sci 2010 ; 123:4374 - 81; http://... - 《Journal of Cell Science》 ...