(1999). Ras pathway is required for the activation of MMP-2 secretion and for the invasion of src-transformed 3Y1. Oncogene 18, 6555- 6563.Thant AA, Sein TT, Liu E, et al. Ras pathway is required for the activa
A. Wnt secretion from epithelial cells and subepithelial myofibroblasts is not required in the mouse intestinal stem cell niche in vivo. Stem Cell Rep. 2, 127–134 (2014). CAS Google Scholar Kabiri, Z. et al. Stroma provides an intestinal stem cell niche in the absence of epithelial Wnt...
Roc Ras-of-complex ROS reactive oxygen species RR ribonucleotide reductase RSV respiratory syncytial virus SARS severe acute respiratory syndrome SARS-3a SARS-CoV ORF protein 3a SDH succinate dehydrogenase siRNA small interfering RNA SNPs (line 657) ssRNA single-stranded RNA T3SS type III secretion sys...
41,42]. Its functionality involves the recognition of a 20nt length specific sequence, as determined by the CRISPR RNA (crRNA) which ends up with the protospacer adjacent motif (PAM) sequence of NGG, and subsequent
(Fig.2). The airway epithelium, from nasal to bronchioles, is coated with mucus, which is a viscous and gel-like secretion. The characteristic viscous, elastic, and adhesive properties of mucus are mainly attributed to mucins. Although many genes encoding mucins have been reported, MUC5AC and...
Cancer cell possesses numerous adaptations to resist the immune system response and chemotherapy. One of the most significant properties of the neoplastic
Ras homolog gene family, member A; ROCK: Rho-associated protein kinase; SOCS: suppressor of cytokine signaling; Smo: transmembrane protein smoothened; STAT: signal transducer and activator of transcription; SUFU: suppressor of fused homolog; TAK: transforming growth factor beta-activated kinase; TNF:...
(Fig. 2d). An extracellular matrix was detected around only the penetration area of the germ tube following dry inoculation of bean leaves and incubation at high humidity (Coleet al., 1996), whereas with conidial suspensions much longer germ tubes and extensive secretion of an extracellular ...
with mutations of the NF1 gene, which encodes the tumor suppressor neurofibromin.42,43These mutations lead to the hyperactivation of the rat sarcoma mitogen-activated protein kinase (RAS-MAPK) pathway, which provokes cell hyperproliferation or tumorigenesis, like neurofibromas, optic pathway gliomas,...
Vitellogenesis (yolk accumulation) begins upon eclosion and continues through the process of sexual maturation. Upon reaching sexual maturity, vitellogenesis is placed on hold until it is induced again by mating. However, the mechanisms that gate vitello