Orchestrating nuclear envelope disassembly and reassembly during mitosis. Nat. Rev. Mol. Cell Biol. 10, 178–191 (2009). PubMed Google Scholar Haraguchi, T. et al. Live cell imaging and electron microscopy reveal dynamic processes of BAF-directed nuclear envelope assembly. J. Cell Sci. 121,...
What are the end products of mitosis?Cell DivisionCell division is necessary for two reasons. The first reason is to generate gametes in a type of cell division called meiosis. The second reason is to replicate somatic cells in a process called mitosis....
In addition, it has also been found that quercetin can inhibit tubular epithelial cell senescence and reduce renal fibrosis by activating SIRT1/PINK1/Parkin-mediated mitosis [28]. Puerarin, a natural product extracted from Radix Puerariae, has been found to have an anti-fibrotic effect in recent...
Explain how the products of mitosis and meiosis occur. What is the end result of the cell cycle and mitosis? How does mitosis work? What is the function of mitosis in the cell? What happens during the stages of mitosis? Describe what happens to the cell and what it looks like...
but steady accumulation of mutations in somatic cells of multicellular organisms. The second limitation of mitotic repair is the need for resources, as each round of mitotic cell division requires DNA and protein synthesis to produce viable daughter cells. Hence, two rounds of mitosis with two ...
Cells may die from accidental cell death (ACD) or regulated cell death (RCD). ACD is a biologically uncontrolled process, whereas RCD involves tightly structured signaling cascades and molecularly defined effector mechanisms. A growing number of novel no
(Fig.4)46. While normally localized in the nucleus, hnRNP L can be translocated into the cytoplasm under hypoxic conditions. Then, hnRNP L can bind to VEGFA in the cytoplasm and inhibit the cellular activity of CARE-binding miRNAs (Fig.4)46. Although this finding was validated in an ...
The epithelial to mesenchymal transition (EMT) has been proposed to contribute to the metastatic spread of breast cancer cells. EMT-promoting transcription factors determine a continuum of different EMT states. In contrast, estrogen receptor α (ERα) helps to maintain the epithelial phenotype of bre...
cell (Zhou et al., 2001). Another cytoprotective property that has been reported for certain tissue-specific stem cells is their ability to differentially segregate newly synthesized chromosomes to more differentiated progeny at mitosis while retaining the original and possibly error-free chromosome ...
Mitotic death is a specific variant of RCD driven by mitotic catastrophe, which suppresses the proliferation of cells undergoing aberrant mitosis60. It usually ends with the formation of large cells with multiple micronuclei and decondensed chromatin166. Ruptured micronuclei can be recognized by CGAS ...