MLLERIAN inhibiting substance (MIS), also known as anti-M眉llerian hormone, is a glycoprotein 14 normally secreted by the Sertoli cells of the fetal and a... RR Behringer,RL Cate,GJ Froelick,... - 《Nature》 被引量: 769发表: 1990年 Mechanisms in vertebrate sex determination - The evolu...
The success of sexual reproduction in mammals depends on segregation of the male sex chromosomes, X and Y, during the cell division process that produces gametes (meiosis). This requires that in male germ cells, the X and Y chromosomes reliably pair and exchange genetic material (1). This pr...
Examples of allostatic load include the accumulation of abdominal fat, the loss of bone minerals and the atrophy of nerve cells in the hippocampus. Studies of the hippocampus as a target of stress and sex hormones have revealed a considerable degree of structural plasticity and remodeling in the ...
During reproductive life, ovarian steroid biosynthesis is gonadotropin dependent and occurs in theca and granulosa cells. In the menopausal ovary, there is atresia of ovarian follicles, with sparing of the androgen-producing theca-interstitial cell component. The aging ovary, therefore, produces significa...
Isolation and characterization of endothelial-to-mesenchymal transition cells in pulmonary arterial hypertension Endothelial-to-mesenchymal transition (EndMT) is a process in which endothelial cells lose polarity and cell-to cell contacts, and undergo a dramatic remod... S Toshio,EJ Carrier,MH Talati,...
Monocrotaline (MCT)-induced pulmonary hypertension (PH) in the rat is a widely used experimental model. We have previously shown that MCT pyrrole (MCTP) produces loss of caveolin-1 (cav-1) and endothelial nitric oxide synthase from plasm... PB Sehgal,S Mukhopadhyay,F Xu,... 被引量: 0发...
A review of 107 titles under the following headings and sub-headings: (1) Learning—experimental: the learning curve; perceptual skill; factors in improvability; cues and methods; special motivation; differences in age, sex, race, etc.; special factors, such as distribution of practice, length...
P-450 17 alpha was localized in luteinized stromal cells in six of these cases--the endometrium of four of which was carcinomatous--while P-450AROM was not present in any case. These results confirm androgen production by the luteinized stromal cells in hyperthecosis, and suggests that ...
In addition to controlling somatic sexual development in Drosophila melanogaster, the Sex-lethal (Sxl) gene is required for proper differentiation of female germ cells. To investigate its role in germ-line development, we have examined the expression of Sxl in wild-type ovaries and ovaries that ar...
Costelytra zealandica (Coleoptera: Scarabeidae) is a univoltine endemic species that has colonised and become a major pest of introduced clover and ryegrass pastures that form about half of the land area of New Zealand. Female beetles were previously shown to use phenol as their sex pheromone ...