Chapter 2 of the section 3 of the book "The Critique of Pure Reason," by Immanuel Kant, translated by J. M. D. Meiklejohn, is presented. It explores the argument of Kant on synthetic a priori truths. It analyzes the antinomy of pure reason. It affirms that the ideas of rational ...
In this study, we sequenced the genomes of 55 Chinese indigenous geese from six breeds. ZE goose, originating from Jilin Province, China, is one of the breeds with the highest egg production in China. HY goose, originating from Liaoning Province, China, is a high egg-producing breed. SC ...
We conducted a genome-wide cytosine methylation analysis of 399 human kidney samples, along with single-nuclear open chromatin analysis on over 60,000 cells from 14 subjects, including controls, and diabetes and hypertension attributed chronic kidney disease (CKD) patients. We identified and validated...
Globally, the production, distribution, sale and consumption of plant-based foods (PBFs) are on the increase due to heightened consumer awareness, a growing demand for clean label products, widespread efforts to promote and embrace sustainable practices,
Muscle-invasive bladder cancer (MIBC) is a highly aggressive disease with a poor prognosis. B cells are crucial factors in tumor suppression, and tertiary lymphoid structures (TLSs) facilitate immune cell recruitment to the tumor microenvironment (TME).
cold weather. These were what helped mammoths survive on the Arctic steppe — ancient chilly grasslands. By adding this DNA to egg cells from Asian elephants, they hope to create an elephant-mammoth mix, which could develop into a baby either inside a living Indian elephant or in a(n)5...
Hadal trenches are the deepest and most remote regions of the ocean. The 11-kilometer deep Challenger Deep is the least explored due to the technical challenges of sampling hadal depths. It receives organic matter and heavy metals from the overlying wate
During the onset of reproductive processes, microbes can be vertically transmitted during oogenesis, either through phagocytosis by oocytes [36] or transmitted via nurse cells [37]. In oviparous sponges, embryonic development occurs in seawater columns after external fertilization [34], facilitating the...
We performed batch correction to merge the three datasets and clustered the cells using an adaptation of the Seurat algorithm12,13 called CellFindR14. CellFindR performs the Seurat algorithm iteratively, first on the entire dataset, producing a set of “Tier 1” clusters, and then on each ...
(miracidia) that seek, infect a suitable snail, and transform into mother sporocysts, the first intra-molluscan developmental stage. Within the mother sporocyst, groups of stem cells (historically termed ‘germinal cells’) start to proliferate and differentiate to develop into daughter sporocysts6. ...