No matter how long the polypeptide is or how intricate the fold, both ends of the chain always end up on the surface. From a topological point of view, this is surprising; one would have expected to find the starting (N-terminal) end inside the core of the folded protein, just as in...
Related to Polypeptide chain:protein pep·tide (pĕp′tīd′) n. Any of various natural or synthetic compounds containing two or more amino acids joined by peptide bonds that link the carboxyl group of one amino acid to the amino group of another. ...
Molten globule state: refers to the polypeptide chain in the structure contains two, without complete tertiary structure of the state. 翻译结果2复制译文编辑译文朗读译文返回顶部 Molten Ball State: when a polypeptide chain contains secondary structure, and not a complete three-level structure of the ...
Polypeptide chain elongation factors have been purified from an extreme thermophile, Thermus thermophilus HB8. By chromatography on a DEAE-Sephadex column, the factors were separated into two peaks; peak I contained a complex of EF-Tu and EF-Ts, while peak II was composed of EF-Tu · GDP an...
The effects of amino acid starvation on regulation of polypeptide chain initiation in Ehrlich ascites tumor cells The ratio of initiation of protein synthesis in Ehrlich ascites tumor cells in culture is reduced by over 60% in the absence of a single essential amino ac... VM Pain,JA Lewis,P...
The polypeptide chain was modeled only tentatively for representation purposes, as the density was very weak. This region is thus not present in the coordinates file deposited in the PDB. (C) Range of Fab elbow angles in selected structures from PDB database, ramp colored from red (smallest,...
To mimic a protein with two monoubiquitin tags, we analyzed degradation of an unmodified substrate containing only the two ubiquitin domains encoded in the polypeptide chain (Ub-35-Ub-GFP-35). This protein was degraded well by wild-type proteasome (Fig. 6b, Supplementary Table 2) and, remarka...
domain. Two residues in the αβ-loop, Ser63 and Ser69, are post-translationally modified in the native PilE39,40. On the opposite side of the β-sheet, the polypeptide chain exits β4 and forms a β-hairpin (β5–β6) that lies atop the β-sheet, followed by an irregular segment...
the gelation increases the density of a substance96. The same things can be applied to the HbS gelation at low pH, which occurs due to the protonation of the HbS polypeptide chain because the protonation not only makes a polymeric chain denser but also provides stiffness to it78. It has al...
Phase improvement by density modification gene rated an interpretable experimental electron density map, which allowed an initial model of the polypeptide chain to be traced using ARP/warp31. Following several alternate cycles of restrained refinement against a maximum likelihood target and manual ...