against NAD+. ATP also inhibits esterase activity in a concentration-dependent manner. The current ALDH1A3 structures at higher resolution will facilitate the rational design of potent and selective inhibitors. ATP binding to ALDH1A3 enables activity modulation by the energy status of the cell and ...
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sodium-potassium-chlo sodiumpotassium atpas sodiumbasebisulfitepu sodiumchloritebleachi sodiumcitrate sodiumiodide131i sodiummethyl-acetylid sodiumnitroprussiate sodiumphosphate32p sodiumpotassium pump sodiumsalt sodiumsulfite sodiumsuperoxide sodiumthiolinate sodiumtriphosphate soe group soeda shuhei soeda takayuki...
2A). This arrangement leaves space for other proteins to bind, and it seemed likely that additional regulators would be involved in controlling a pathway that can account for 15% of the cell's ATP flux. There is some evidence for effects (direct or indirect) of other regulators on gltBDF ...
P-type ATPases constitute a large group of membrane-embedded, ATP-dependent, active transporters, that build up and maintain concentration gradients across membranes. The copper transporters belong to the heavy metal-specific P1B-subclass (P1B-ATPases), as part of the P1B-1-ATPases subfamily,...
Drozak J, Veiga-da-Cunha M, Vertommen D et al (2010) Molecular identification of carnosine synthase as ATP-grasp domain-containing protein 1 (ATPGD1). J Biol Chem 285:9346–9356 ArticleGoogle Scholar Du J, Cullen JJ, Buettner GR (2012) Ascorbic acid: chemistry, biology and the treatment...
The P2X7 receptor, originally known as the P2Z receptor due to its distinctive functional properties, has a structure characteristic of the ATP-gated ion channel P2X receptor family. The P2X7 receptor is an important mediator of ATP-induced purinergic signalling and is involved the pathogenesis of...
We carried out end repair of 5′ and 3′ ends of fragmented RNAs for library preparation. End repair was carried out using T4 Polynucleotide Kinase (NEB, cat. #MO201S) that catalyzes the transfer and exchange of Pi from the gamma position of ATP to the 5′-hydroxyl termini of the RNA...
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Layout of the model of acidity control in tumor cells. A cell takes up from the environment nutrients and oxygen which are then converted by cell metabolism to lactic acid,CO2and ATP. Lactic acid dissociates to lactate andH+ions, whereasCO2reversibly hydrates toHCO3−andH+. These chemical ...