one originating in epithelium, tending to recur after excision and to metastasize to other sites. b. any disease characterized by such growths. 2. any evil condition or thing that spreads destructively; blight. 3. (cap.) the Crab, a zodiacal constellation between Gemini and Leo. 4. ...
The thin, protective layer of cells that covers most of the outer surface of an animal body and lines the inner surface of many body parts. In vertebrate animals, the outer layer of the skin, called the epidermis, is composed of epithelium. ...
2011. Activity of the ovarian germinal epithelium in the freshwater catfish, Pimelodus maculatus (Teleostei: Ostariophysi: Siluriformes): germline cysts, follicle formation and oocyte development. Journal of Morphology, 272: 1290-1306.Quagio-Grassiotto I., Grier H., Mazzoni T.S., Nobrega R.H....
The transcriptional activity of ERα can be switched on by both cognate ligand and ligand-independent pathways to regulate cell functions in the mammary epithelium30. The binding of 17β-estradiol (E2) to its hormone-binding domain (HBD) triggers the binding of an ERα homodimer to specific ...
Ovary is the female reproductive organ that consists of epithelium, germ cell, and ovarian stroma components (Elsherif et al. 2019). There are two subtypes of ovarian cancer: Type 1 (low-grade) carcinoma includes serous, clear cell, endometrioid and mucinous carcinoma, which represents 25 % of...
Understanding the mechanistic effects of novel immunotherapy agents is critical to improving their successful clinical translation. These effects need to be studied in preclinical models that maintain the heterogenous tumor microenvironment (TME) and dys
Microfluidic chips for ovarian follicles.aThe ovary is composed of the reproductive epithelium, tunica albuginea, cortex, and medulla. Among them, the cortex is the outer layer of the ovary, including follicles, mesenchyme and antral cavity. The medulla is the inner region of the ovary, which is...
A healthy intestinal epithelium acts as a barrier to preventing the migration of bacterial-derived factors and prevents LPS from entering the systemic circulation [103]. However, high-fat diets disrupt intestinal barrier function, allowing LPS translocation. This condition, called metabolic endotoxemia, ...
ovarian cyst - a cystic tumor (usually benign) of the ovary ranula - a cyst on the underside of the tongue pilar cyst, sebaceous cyst, steatocystoma, wen - a common cyst of the skin; filled with fatty matter (sebum) that is secreted by a sebaceous gland that has been blocked patholog...
Aberrant regulation or activation of the PI3K/Akt/mTOR cascade is mainly involved in the development of various human cancers such as acute lymphoma (AML), T cell acute lymphoblastic leukemia (T-ALL), breast cancer, ovarian cancer, prostate cancer, and mantle cell lymphoma [91,92,93,94]. ...