9. LeGrand S, Scheinberg A, Tillack AF, Thavappiragasam M, Vermaas JV, Agarwal R, Sedova A (2020) GPU-accelerated drug discovery with docking on the summit supercomputer: porting, optimization, and application to COVID-19 research. In: Proceedings of the 11th ACM international conference o...
This chapter discusses the development from the origin and current status to the future prospect in microfluidics including: development of microfluidic components; development of complex microfluidic systems; and development of application-oriented microfluidic systems. Because of the advantage of easy ...
hurdle. Many conventional techniques lack accuracy, effectiveness, and practicality; yet microfluidic technology has the potential to simplify and improve S-EV isolation and detection. Key points Epididymosomes and prostasomes, the two distinct populations of seminal plasma small extracellular vesicles (S...
27 These lines could be readily expanded in uniform growth medium containing Wnt3a, R-spondin and Noggin, and maintained their origin-specific expression patterns upon differentiation. While the authors did not conduct absorption studies, the formation of polarized monolayers and the presence of a ...
Extracellular vesicles have shown promising tissue recovery-promoting effects, making them increasingly sought-after for their therapeutic potential in wound treatment. However, traditional extracellular vesicle applications suffer from limitations such
The main drawback of these devices lies in the manual assembly, making them expensive for mass production. Integrated devices, with both microfluidics and photonics fully integrated on-chip, have been demonstrated as well, but their operation has been limited to the discrimination of microbeads or ...
Axiovert confocal microscope or a Leica Dmi8 inverted microscope. Primary hFBs obtained from the collections of biological samples of human origin registered in the ‘Registro Nacional de Biobancos para Investigación Biomédica del Instituto de Salud Carlos III’. Both normal and fluorescent cells ...
Understanding the characteristics and structure of populations is fundamental to comprehending ecosystem processes and evolutionary adaptations. While the study of animal and plant populations has spanned a few centuries, microbial populations have been
et al. Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells. Cell Stem Cell 14, 53–67 (2014). CAS PubMed Google Scholar Bantounas, I. et al. Generation of functioning nephrons by implanting human ...
The physical microenvironment of tumours is characterized by heterotypic cell interactions and physiological gradients of nutrients, waste products and oxygen. This tumour microenvironment has a major impact on the biology of cancer cells and their response to chemotherapeutic agents. Despite this, most in...