. (2002) "The next decade of research in basic mechanisms of the epilepsies," in Jasper's Basic Mechanisms of the Epilepsies, (Oxford: Oxford University Press), 3-11.Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV. The next decade of research in the basic mechanisms of...
Over the past decade, the field of metabolism has witnessed remarkable scientific discoveries that reshaped the understanding of metabolic physiology and disease. As we launch Nature Metabolism, we look at what the future holds for metabolic research. This is a preview of subscription content, ...
A year later, the first recombinant protein, insulin, was reported by Genentech. Goeddel et al.4 synthesized insulin from two separately cloned polypeptide chains demonstrating for the first time synthetic recombinant technology to produce a therapeutic protein. Over the next decade, protein ...
We are at a pivotal moment in the development of these therapies; the next decade will bring enormous changes to usher cell, gene and RNA therapies into the pharmacotherapeutic mainstream. Contact Us Investor Relations Customer Portal Careers Code of Conduct Events Contact Us Third-Pa...
In this Review, we provide an overview of the current state of protein corona research in nanomedicine. We next discuss remaining challenges in the research methodology and characterization of the protein corona that slow the development of nanoparticle therapeutics and diagnostics, and we address how...
"I am proud that all our athletes in the Hong Kong, China Delegation have competed in the true spirit of the Olympic motto, 'faster, higher, stronger—together.' As the Belt and Road Initiative ushers in its next golden decade, I believe this spirit can be applied to our mission here ...
Prof. Bing Renis the Fellow of the American Association for the Advancement of Science. He is currently the Director of Center for Epigenomics at UC San Diego, and Member of Ludwig Institute for Cancer Research. Dr. Ren has been at the forefront of epigenomic research for over a decade. He...
Acta Tropica 238 (2023) 106750 Contents lists available at ScienceDirect Acta Tropica journal homepage: www.elsevier.com/locate/actatropica A retrospective analysis of schistosomiasis related literature from 2011-2020: Focusing on the next decade ...
Despite this large body of information, GPCRs were generally not thought to represent traditional “genetic drivers” in cancer, thus pursuing GPCRs in oncology was neglected for some time. In the past decade, however, studies bloomed linking GPCRs to many cancers and mechanisms of tumorigenesis,...
Fig. 1: MutPred2 and the molecular consequences of amino acid substitutions. a The human tumor suppressor p53 as an illustration of the numerous possible effects of amino acid substitutions on protein structure and function. Protein Data Bank IDs for the structures shown are 1TUP, 1YCS, 2J1W...