All data were analysed statistically by unpaired Student’s two-tailed t-test or one-way analysis of variance with Tukey’s correction for multiple comparisons using GraphPad Prism version 6.0 f for Mac, GraphPad Software, La Jolla, CA, USA. In all tests, values of P<0.05 were considered...
Epilepsy and autism spectrum disorders (ASD) are two distinct brain disorders but have a high rate of co-occurrence, suggesting shared pathogenic mechanisms. Neuroligins are cell adhesion molecules important in synaptic function and ASD, but their role i
5 Alzheimer's Disease Research Center, Department of Neurology, School of Medicine, University of California Davis, Sacramento, CA, USA. 6 Department of Neurosciences, University of California San Diego, La Jolla, San Diego, CA, USA. Received: 14 March 2023 Accepted: 30 April ...
Statistical analysis was performed using the GraphPad Prism (version 8.0; GraphPad Software La Jolla, CA, USA). All statistical tests and group size (n) are indicated in the figures. To account for multiple observations within the imaged mouse, results from each group were compared using ...
Please join us at our ICM User Group Meeting on April 9th and 10th to be held in La Jolla, CA. Come and hear about the latest developments in: Structure and Ligand Based Drug Design, Membrane Protein Modeling, Protein Structure Analysis, Virtual Ligand Screening, Protein-Protein Docking, Data...
Elena R. CuttingUniversity of California San Diego, San Diego, CAShumei KatoUniversity of California San Diego, Moores Cancer Center, La Jolla, CAWilliam M. MitchellSan Diego Moores Cancer Center, La Jolla, CABenjamin Michael HeymanSan Diego Health, La Jolla, CA...
Statistical analysis was performed and plotted using GraphPad Prism 9 (GraphPad, La Jolla, CA). An unpaired t test was used to test for statistical significance between two nonpaired normally distributed data groups. The statistical significance in parametric multiple comparisons was tested by Tukey’...
Department of Neurology, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, 15232, USA Jeremy N. Rich Department of Pathology, School of Medicine, University of California, San Diego, La Jolla, CA, 92093, USA Aaron F. Carlin ...
La Jolla, CA, USA; 2Section of Pharmacology, Department of Medicine and Public Health, University of Verona, Verona, Italy; 3Lilly Centre for Cognitive Neuroscience, Lilly Research Laboratories, Eli Lilly and Co., Ltd., Erl Wood Manor, Windlesham, UK; 4Department of Psychiatry, Research and ...
23, 2014, is named CA206392_SL.txt and is 85,365 bytes in size. FIELD OF THE INVENTION The present invention relates to reducing or inhibiting the function and/or signaling through the low density lipoprotein receptor-related protein-1 (LRP-1) to promote, enhance and/or restore neuron ...