The movement of molecules across membranes is discussed in terms of thermal fluctuations in the hydrocarbon chains of the membrane lipids. The thermal motion of the hydrocarbon chains results in the formation of conformational isomers, so-called kink-isomers of the hydrocarbon chains. "Kinks" may be...
杨四军副教授糖尿病国内大咖专家英文专题报告The Movement of Substances Across Cell Membranes.ppt,Yang Sijun Ph.D Pro of pathologyThe Movement of Substances Across Cell Membranes A motor neuron cell body in the spinal cord. (A) Many thousands of nerve termi
The movement of Lys4563 is indicated by a red arrow, while the interaction between Lys4563 and Asp4815 is shown with a red dashed line. d, e Comparison of the diamide-binding sites in closed ref-chiRyR (ref-chiRyR-closed-HM: a homology model based on closed rRyR1 (PDB 5TAQ)), ...
The transport of small molecules through a polymer membrane is modeled using the computer simulation technique of molecular dynamics (MD). The transport coefficient is derived from a combination of the excess free energy and the diffusion constant. Both properties are derived from MD simulations, appl...
of the BBB responsible for selective permeability to small lipophilic molecules [7]. These cells tightly bind together to prevent paracellular drug transport across the BBB and contribute to the high transendothelial resistance (TEER) that limits the passive diffusion of external compounds between the ...
Guided by gut sensory cues, humans and animals prefer nutritive sugars over non-caloric sweeteners, but how the gut steers such preferences remains unknown. In the intestine, neuropod cells synapse with vagal neurons to convey sugar stimuli to the brain
The human translocase of the outer membrane (TOM) is a multi-subunit protein complex located in the outer mitochondrial membrane of the mitochondria, which is involved in the recognition, unfolding, and translocation of preproteins into the mitochondria. ...
Microtubules provide tracts along which membrane bounded vesicles travel to and from the plasma membrane.The directional movement of these cargo vesicles is due to a family of motor proteins linking vesicles and microtubules.membrane bounded organelles like mitochondria are loosely trapped by the ...
Mitochondrial energy conversion requires an intricate architecture of the inner mitochondrial membrane1. Here we show that a supercomplex containing all four respiratory chain components contributes to membrane curvature induction in ciliates. We report
flagella in the periplasmic space11. It is believed that the rotation of the periplasmic flagella (PFs) beneath the outer membrane drives the rolling of the spiral body12. The PF-dependent rotation of the cell body produces the thrust needed to swim in liquid media and crawl on a solid ...