Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous system (CNS) from toxins and pathogens in blood. However, the presence of BBB complicates the pharmacotherapy for CNS disorders as the most chemical drugs and biopharmaceuticals have been impeded to enter the...
New Molecule Found to Cross the Blood-Brain BarrierAnis unavailable. This article is available as HTML full text and PDF.doi:10.1097/01.NT.0000367466.11687.41TOM VALEONeurology Today
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is known to contain an active-site cysteine residue undergoing oxidation in response to hydrogen peroxide, leading to rapid inactivation of the enzyme. Here we show that human and mouse cells expressing a GAPDH mutant lacking this redox switch retain ...
Red blood cells are one of the formed elements of the blood other than platelets and white blood cells. The production of red blood cells from hemocytoblasts in the red bone marrow is regulated by the hormone erythropoietin.Answer and Explanation: The molecule in the red bloo...
The blood–brain barrier (BBB) is a sophisticated structure whose full functionality is required for maintaining the executive functions of the central nervous system (CNS). Tight control of transport across the barrier means that most drugs, particularly large size, which includes powerful biologicals...
Blood is the most common type of specimen for POC testing. However, the cellular components in whole blood often cause non-specific background. To address this problem, a continuous microfluidic device was developed to filter the cells, making plasma available for on-chip analysis [99]. ...
increases plasma nitrate and nitrite levels for several hours after nitrate intake, thereby enhancing nitric oxide bioavailability11 Among the most studied outcomes of consuming nitrate-rich vegetables, particularly beetroot juice, is the acute reduction in blood pressure observed 1–3 h post-ingestion12...
Blood: Blood can be described as a specialized body fluid. The main components of blood are erythrocytes (also called red blood cells), plasma, leukocytes (also called white blood cells), and thrombocytes. Answer and Explanation: The correct answer ...
Depressive neurosis belongs to the category of “depression syndrome” in traditional Chinese medicine. The classic Chinese medical text ‘Danxi's Experiential Therapy: Six Depressions’ proposed that “qi and blood in coordination, all diseases do not arise; when there is depression, various diseases...
3B). The different classification is most likely due to the different convalescent serum used as detection reagents. These same antiviral data were also analysed using Synergyfinder, which also indicated that the two drugs were additive to synergistic, with a representative graph shown in Fig. 3B....