The most abundant collagens are the fibrillar types (I, II, III, V, and XI) and their extensive cross-linking provides mechanical strength that is necessary for high stress tissues such as cartilage, bone, and skin. Another group of collagens are the fibril associated collagens with ...
OYs, the most abundant sub-population of bone cells, are the least-studied cell type. Current research suggests that sclerostin is a very important molecule. Micro-damage causes sclerostin shut-down and triggers bone remodelling. However, it is not clear whether sclerostin is present in a free ...
The development of skeletal muscle in pigs during the embryonic stage is precisely regulated by transcriptional mechanisms, which depend on chromatin accessibility. However, how chromatin accessibility plays a regulatory role during embryonic skeletal muscle development in pigs has not been reported. To ga...
covers the articular cartilage. Since the blood supply from the epiphyseal arteries has no direct access to the medullary region, they tend to enter via extensive networks in the peri-articular vascular plexus. This plexus helps maintain isolated blood circulation, which is essential for skeletal gro...
(Fig.1cand Supplementary Fig.1c). Fibroblasts were identified by their archetypal markersLUM,DCN,VIM,PDGFRA, andCOL1A227, constituted the most abundant skin cell type (5948 cells in total), and were represented by four clusters (#1, #2, #3, and #9, Fig.1cand Supplementary Fig.1c)....
The overlap is particularly evident for the most abundant core matrisome proteins belonging to the collagen and proteoglycan categories (Fig. 4A, right panel). Therefore, to define the extracellular matrix composition of a tissue, we combined the data from two independent samples including only those...
Collagen is more than a profile and that's what we here offer you with VEGCOL™ This is neither an 'amino acid blend', nor a 'builder' Vital Collagen in the Body Collagen is a fundamental component of the human body as the most abundant protein. Its presence is ubiquitous across ...
The osmolyte taurine is the most abundant free amino acid in cardiac tissues and in skeletal muscle. In response to hyper-osmotic stress, cells take up taurine to counter the elevations in extracellular osmolarity. One mechanism responsible for the intracellular taurine accumulation is the NFAT5-medi...
Moreover, there is evidence that both types are involved in remote I/R injury as well [6]. Therefore, in the next step we aimed to determine the activities of MMP-2 and MMP-9, the most abundant MMP types in the myocardium, from plasma samples with gelatin zymography. By gelatin ...
The ribosome has long been considered as a consistent molecular factory, with a rather passive role in the translation process. Recent findings have shifted this obsolete view, revealing a remarkably complex and multifaceted machinery whose role is to or