Neutrophils, as the most abundant leukocytes, are heterogeneous cell population with high functional plasticity. In general, neutrophils act as the first defence line of immune system, which have a high potency and efficacy to sense and eradicate pathogen infections. Although historically they are cons...
are the disease-fighting components of blood. They account for just 1% of circulating blood but multiply during infection or inflammation. There are five types of white blood cells: neutrophils, eosinophils, basophils, lymphocytes, and monocytes. Neutrophils are the most abundant, comprising 60% to...
INTRODUCTION Polymorphonuclear leukocytes (PMN), also called neutrophils, are the most abundant leukocyte population in the blood, com- prising 50–60% of the circulating leukocytes (25×109 cells).1 PMN are critical components of the innate immune response that are essential in protecting the host...
After dNK cells, macrophages are the most abundant leukocytes5, and we examined the cellular heterogeneity of macrophages in the decidual immune microenvironment. We detected two subsets of macrophages from a total of 3406 single-macrophage transcriptomes: mac1 and mac2 (Fig.4a). Recalling our init...
Further clinical trials are also essential to validate these findings and translate them into effective therapeutic strategies. In acute kidney injury (AKI) TECs are the most abundant cell type in the kidney and play a crucial role in pathological renal injuries. Tubulointerstitial inflammation is a ...
Cells resembling macrophages or transitional forms between monocytes and macrophages are occasionally seen. Blood eosinophils and basophils are not found. Thrombocytes and small lymphocytes are the most abundant leukocytes, while monocytes are the least frequently encountered leukocyte. Glycogen, present ...
[13]. Thus, the name we use to refer to the most abundant immune cell population in the uterus is effectively a misnomer. Nevertheless, in an era of immunology when more immune cell subsets are discovered and renamed than we can keep up with [14], it may be wiser to resist the ...
Kiwifruit contain several unique proteins and the cysteine protease actinidin, the most abundant protein in kiwifruit, of interest for their bioactive potential. The characterisation and biochemical properties of actinidin have been extensively studied [92,93], and more recently its potential role in hum...
This finding is important because neutrophils, the most abundant leukocytes in the circulation, are the first line of defense in the innate immune system64. Neutrophils quickly respond to invading micro- organism and trap and kill the invading pathogens by phagocytosis, degranulation, and the release...
There are more than 10 different cell types with various functions in hematopoietic system. For examples, leukocytes are mainly involved in innate and acquired immunity; erythrocytes provide O2and CO2exchange and transport; megakaryocytes generate platelets during wound healing. Most importantly, hematopoie...