The Goombas of World 5-3 use a device known as the Goomba's Shoe (also known as the Kuribo's Shoe) to mimic the jumping abilities of Mario and Luigi. When in the green shoe, a Kuribo's Goomba can jump towards Mario and Luigi instead of walking into them. If Mario or Luigi defeats...
Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc. Natl Acad. Sci. USA 110, 3507–3512 (2013). CAS PubMed PubMed Central Google Scholar Takao, K. & Miyakawa, T. Genomic responses in mouse models greatly mimic human inflammatory diseases. Proc. Natl Acad. Sci...
Traditional antidepressants largely interfere with monoaminergic transport or degradation systems, taking several weeks to have their therapeutic actions. Moreover, a large proportion of depressed patients are resistant to these therapies. Several atypic
The mechanism of memory remains one of the great unsolved problems of biology. Grappling with the question more than a hundred years ago, the German zoologist Richard Semon formulated the concept of the engram, lasting connections in the brain that resul
The viral community has the potential to influence the structure of the microbiome and thus the yield of the anaerobic digestion process. However, the virome composition in anaerobic digestion is still under-investigated. A viral induction experiment was
This finding was not observed for dorsal hippocampal CA1 (dCA1). The overexpression of human tau (hTau) in excitatory and PV neurons mimicked AD-like tau accumulation, significantly inhibited neuronal excitability and suppressed distinct discrimination-associated firings of these neurons within vCA1....
Scryfall runs the Tagger project, which allows Scryfall supporters in the community to tag the artwork and functional pieces of each Magic card. We import these tags daily, and you can search for them on Scryfall.
most animal models mimic only mania or depression and only a few include the cyclical nature of the human condition. Future studies could therefore focus on modeling both episodes in the same animal model to also have the possibility to investigate the switch from mania-like behavior to depressive...
Although the molecular mechanism underlying the neuroprotective effect of PEA needs further investigations, we provided evidence suggesting that PEA acting at PPAR-a rescues behavioral impairments that can mimic some traits of AD. Considering that PEA is currently used to treat chronic pain, our ...
For water maze experiments, animals were given four consecutive trials with randomized entry points in a round pool filled with opaque water. Each trial lasted 1 min. If the animals did not find the platform within this time, they were gently guided to the platform and allowed to stay on...