The same samples extracted at different times, diluted or undiluted before amplification, or sequenced in different runs showed high reproducibility, indicating that random contamination had no major impact on bacterial community structure detected in the upper reproductive tract (Supplementary Table2, Suppl...
bacterial translocation, migration of gut-primed lymphocytes to the liver, bile acids and nuclear receptor signaling are involved in PBC and PSC pathogenesis. Cyp7a1, cholesterol 7 alpha-hydroxylase; Fgf15, fibroblast growth factor 15; MAMPs, microbe-associated molecular patterns; UDCA...
The Lancet Microbe publishes research on clinically relevant microbes at all scales?from the nature of the microbe (eg, antimicrobial resistance genes/plasmids, virulence factors) to the microbiome, to pathology (including immunology) to population level effects (eg, outbreaks, epidemiology). … View...
The Lancet Microbe publishes clinically relevant microbes at all scales—from the nature of the microbe (eg, antimicrobial resistance genes/plasmids, virulence factors) to the microbiome, to pathology (including immunology) to population level effects (eg, outbreaks, epidemiology). We also publish earl...
Microbe isolation and in vitro growth detection To isolateMassilia, bacteria showing positive responses to root exudates of the high-oil cultivars, we treated the soil with root exudates from Hefeng52 as described above; and gradient dilutions were prepared and plated on minimal medium (MM; 0.5 ...
“Danger” signals are released after tissue injury (from self-tissues, called “damage-associated molecular patterns”) or after exposure to microorganisms/pathogens (from infected tissues, called “pathogen-associated molecular patterns”) or commensals (called “microbe-associated molecular patterns”)....
In fact, our lab has recently shown that microbe-metabolite correlations have extremely high false positive rates in predicting mechanistic links in simulated data [36]. Second, in the context of case-control studies, it is often unclear how the association is related to the phenotype/disease ...
Microbial composition and structures variation were significantly impacted by local environmental conditions, and soil C/N is the most important factor to impact the microbial structure in alpine meadow in Qinghai-Tibetan plateau.Background Microorganisms are the most abundant and diverse groups of ...
B. The role of the immune system in governing host-microbe interactions in the intestine. Nat. Immunol. 14, 660–667 (2013). Article CAS PubMed Google Scholar McDole, J. R. et al. Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine. Nature 483, 345...
Furusawa, Y. et al. Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells.Nature504, 446–450 (2013). ArticleCASADSGoogle Scholar Zhong, Y., Marungruang, N., Fåk, F. & Nyman, M. Effects of two whole-grain barley varieties on caecal SCFA, gut mi...